Teronac
Brand names,
Teronac
Analogs
Teronac
Brand Names Mixture
- For sope (sodium lauryl sulfate + stearic acid)
- Plax anti-plaque den rinse peppermint liq (sodium benzoate + sodium lauryl sulfate + sodium salicylate)
- Plax anti-plaque dent rinse soft mint liq (sodium benzoate + sodium lauryl sulfate + sodium salicylate)
- Plax anti-plaque dental rinse (sodium benzoate + sodium lauryl sulfate + sodium salicylate)
Teronac
Chemical_Formula
C15H22N2O
Teronac
RX_link
http://www.rxlist.com/cgi/generic2/mepivacaine.htm
Teronac
fda sheet
Teronac
msds (material safety sheet)
Teronac
Synthesis Reference
No information avaliable
Teronac
Molecular Weight
246.348 g/mol
Teronac
Melting Point
150.5 oC
Teronac
H2O Solubility
Soluble (7000 mg/L)
Teronac
State
Solid
Teronac
LogP
2.674
Teronac
Dosage Forms
Liquid; Solution
Teronac
Indication
For production of local or regional analgesia and anesthesia by local infiltration, peripheral nerve block techniques, and central neural techniques including epidural and caudal blocks.
Teronac
Pharmacology
Mepivicaine is a local anesthetic of the amide type. Mepivicaine as a reasonably rapid onset and medium duration and is known by the proprietary names as Carbocaine and Polocaine. Mepivicaine is used in local infiltration and regional anesthesia. Systemic absorption of local anesthetics produces effects on the cardiovascular and central nervous systems. At blood concentrations achieved with normal therapeutic doses, changes in cardiac conduction, excitability, refractoriness, contractility, and peripheral vascular resistance are minimal.
Teronac
Absorption
Absorbed locally. The rate of systemic absorption of local anesthetics is dependent upon the total dose and concentration of drug administered, the route of administration, the vascularity of the administration site, and the presence or absence of epinephrine in the anesthetic solution.
Teronac
side effects and Toxicity
The mean seizure dosage of mepivacaine in rhesus monkeys was found to be 18.8 mg/kg with mean arterial plasma concentration of 24.4 µg/mL. The intravenous and subcutaneous LD 50 in mice is 23 mg/kg to 35 mg/kg and 280 mg/kg respectively.
Teronac
Patient Information
Teronac
Organisms Affected
Humans and other mammals