Mechothane
Brand names,
Mechothane
Analogs
Mechothane
Brand Names Mixture
Mechothane
Chemical_Formula
C7H17N2O2
Mechothane
RX_link
http://www.rxlist.com/cgi/generic3/bethane.htm
Mechothane
fda sheet
Mechothane
msds (material safety sheet)
Mechothane
Synthesis Reference
No information avaliable
Mechothane
Molecular Weight
161.222 g/mol
Mechothane
Melting Point
217-221 oC (chloride salt)
Mechothane
H2O Solubility
10 mg/mL (chloride salt)
Mechothane
State
Solid
Mechothane
LogP
No information avaliable
Mechothane
Dosage Forms
Tablet
Mechothane
Indication
For the treatment of acute postoperative and postpartum nonobstructive (functional) urinary retention and for neurogenic atony of the urinary bladder with retention.
Mechothane
Pharmacology
Bethanechol is a parasympathomimetic (cholinergic) used for the treatment of acute postoperative and postpartum nonobstructive (functional) urinary retention and for neurogenic atony of the urinary bladder with retention. Bethanechol, a cholinergic agent, is a synthetic ester which is structurally and pharmacologically related to acetylcholine. It increases the tone of the detrusor urinae muscle, usually producing a contraction sufficiently strong to initiate micturition and empty the bladder. It stimulates gastric motility, increases gastric tone, and often restores impaired rhythmic peristalsis. Bethanechol chloride is not destroyed by cholinesterase and its effects are more prolonged than those of acetytcholine.
Mechothane
Absorption
No information avaliable
Mechothane
side effects and Toxicity
No information avaliable
Mechothane
Patient Information
Bethanechol chloride tablets should preferably be taken one hour before or two hours after meals to avoid nausea
or vomiting. Dizziness, lightheadedness or fainting may occur, especially when getting up from a lying or sitting
position.
Mechothane
Organisms Affected
Humans and other mammals