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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C7H17N2O2
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RX_link
http://www.rxlist.com/cgi/generic3/bethane.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
161.222 g/mol
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Melting Point
217-221 oC (chloride salt)
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H2O Solubility
10 mg/mL (chloride salt)
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State
Solid
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LogP
No information avaliable
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Dosage Forms
Tablet
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Indication
For the treatment of acute postoperative and postpartum nonobstructive (functional) urinary retention and for neurogenic atony of the urinary bladder with retention.
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Pharmacology
Bethanechol is a parasympathomimetic (cholinergic) used for the treatment of acute postoperative and postpartum nonobstructive (functional) urinary retention and for neurogenic atony of the urinary bladder with retention. Bethanechol, a cholinergic agent, is a synthetic ester which is structurally and pharmacologically related to acetylcholine. It increases the tone of the detrusor urinae muscle, usually producing a contraction sufficiently strong to initiate micturition and empty the bladder. It stimulates gastric motility, increases gastric tone, and often restores impaired rhythmic peristalsis. Bethanechol chloride is not destroyed by cholinesterase and its effects are more prolonged than those of acetytcholine.
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Absorption
No information avaliable
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side effects and Toxicity
No information avaliable
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Patient Information
Bethanechol chloride tablets should preferably be taken one hour before or two hours after meals to avoid nausea
or vomiting. Dizziness, lightheadedness or fainting may occur, especially when getting up from a lying or sitting
position.
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Organisms Affected
Humans and other mammals