Besacholine
Brand names,
Besacholine
Analogs
Besacholine
Brand Names Mixture
Besacholine
Chemical_Formula
C7H17N2O2
Besacholine
RX_link
http://www.rxlist.com/cgi/generic3/bethane.htm
Besacholine
fda sheet
Besacholine
msds (material safety sheet)
Besacholine
Synthesis Reference
No information avaliable
Besacholine
Molecular Weight
161.222 g/mol
Besacholine
Melting Point
217-221 oC (chloride salt)
Besacholine
H2O Solubility
10 mg/mL (chloride salt)
Besacholine
State
Solid
Besacholine
LogP
No information avaliable
Besacholine
Dosage Forms
Tablet
Besacholine
Indication
For the treatment of acute postoperative and postpartum nonobstructive (functional) urinary retention and for neurogenic atony of the urinary bladder with retention.
Besacholine
Pharmacology
Bethanechol is a parasympathomimetic (cholinergic) used for the treatment of acute postoperative and postpartum nonobstructive (functional) urinary retention and for neurogenic atony of the urinary bladder with retention. Bethanechol, a cholinergic agent, is a synthetic ester which is structurally and pharmacologically related to acetylcholine. It increases the tone of the detrusor urinae muscle, usually producing a contraction sufficiently strong to initiate micturition and empty the bladder. It stimulates gastric motility, increases gastric tone, and often restores impaired rhythmic peristalsis. Bethanechol chloride is not destroyed by cholinesterase and its effects are more prolonged than those of acetytcholine.
Besacholine
Absorption
No information avaliable
Besacholine
side effects and Toxicity
No information avaliable
Besacholine
Patient Information
Bethanechol chloride tablets should preferably be taken one hour before or two hours after meals to avoid nausea
or vomiting. Dizziness, lightheadedness or fainting may occur, especially when getting up from a lying or sitting
position.
Besacholine
Organisms Affected
Humans and other mammals