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Lorfan Brand names, Lorfan Analogs

Lorfan Brand Names Mixture

  • No information avaliable

Lorfan Chemical_Formula


Lorfan RX_link

No information avaliable

Lorfan fda sheet

Lorfan msds (material safety sheet)

Lorfan Synthesis Reference

Schnider, et al., Helv. Chim. Acta. 34, 2211 (1951)

Lorfan Molecular Weight

283.408 g/mol

Lorfan Melting Point

181 oC

Lorfan H2O Solubility

633 mg/L

Lorfan State


Lorfan LogP


Lorfan Dosage Forms

Solution for injection (intramuscular, subcutaneous or intravenous)

Lorfan Indication

For the complete or partial reversal of narcotic depression, including respiratory depression, induced by opioids.

Lorfan Pharmacology

Levallorphan, an opioid antagonist similar to naloxone, is used to treat drug overdoses. Levallorphan differs from naloxone in that it also possesses some agonist properties. It is an analogue of levelorphanol that counteracts the actions of narcotic analgesics such as morphine. It is used especially in the treatment of respiratory depression due to narcotic overdoses. Levallorphan prevents or reverses the effects of opioids including respiratory depression, sedation and hypotension. Also, it can reverse the psychotomimetic and dysphoric effects of agonist-antagonists such as pentazocine.

Lorfan Absorption

Rapidly absorbed.

Lorfan side effects and Toxicity

Oral, rat LD50: 109±4 mg/kg

Lorfan Patient Information

No information avaliable

Lorfan Organisms Affected

Humans and other mammals