Levallofano [Dcit] en es it fr

Levallofano [Dcit] Brand names, Levallofano [Dcit] Analogs

Levallofano [Dcit] Brand Names Mixture

  • No information avaliable

Levallofano [Dcit] Chemical_Formula

C19H25NO

Levallofano [Dcit] RX_link

No information avaliable

Levallofano [Dcit] fda sheet

Levallofano [Dcit] msds (material safety sheet)

Levallofano [Dcit] Synthesis Reference

Schnider, et al., Helv. Chim. Acta. 34, 2211 (1951)

Levallofano [Dcit] Molecular Weight

283.408 g/mol

Levallofano [Dcit] Melting Point

181 oC

Levallofano [Dcit] H2O Solubility

633 mg/L

Levallofano [Dcit] State

Solid

Levallofano [Dcit] LogP

4.546

Levallofano [Dcit] Dosage Forms

Solution for injection (intramuscular, subcutaneous or intravenous)

Levallofano [Dcit] Indication

For the complete or partial reversal of narcotic depression, including respiratory depression, induced by opioids.

Levallofano [Dcit] Pharmacology

Levallorphan, an opioid antagonist similar to naloxone, is used to treat drug overdoses. Levallorphan differs from naloxone in that it also possesses some agonist properties. It is an analogue of levelorphanol that counteracts the actions of narcotic analgesics such as morphine. It is used especially in the treatment of respiratory depression due to narcotic overdoses. Levallorphan prevents or reverses the effects of opioids including respiratory depression, sedation and hypotension. Also, it can reverse the psychotomimetic and dysphoric effects of agonist-antagonists such as pentazocine.

Levallofano [Dcit] Absorption

Rapidly absorbed.

Levallofano [Dcit] side effects and Toxicity

Oral, rat LD50: 109±4 mg/kg

Levallofano [Dcit] Patient Information

No information avaliable

Levallofano [Dcit] Organisms Affected

Humans and other mammals