LEVOMYSOL

• Anti-Infective Agents
• Antibacterial Agents
• Protein Synthesis Inhibitors
• ATC:J01XX08

• Ergamisol
• Ketrax
• L-Tetramisole
• LEVOMYSOL
• Lepuron
• Levamisol
• Levamisol [INN-Spanish]
• Levamisole Tetramisole
• Levamisolum [INN-Latin]
• Nilverm base
• Phenyl imidothiazole
• Tetramisol
• Tetramisole
• Tramisol
• Vermisol 150
• Wormicid
• dl-Tetramisol
• dl-Tetramisole

• No information avaliable

C₁₆H₂₀FN₃O₄

http://www.rxlist.com/cgi/generic3/linezolid.htm

LEVOMYSOL FDA

LEVOMYSOL MSDS

No information avaliable

337.346 g/mol

No information avaliable

3 mg/mL

Solid

0.232

Solution; Tablets

For the treatment of bacterial infections caused by susceptible strains of vancomycin resistant Enterococcus faecium, Staphylococcal aureus (methicillin resistant and susceptible strains), Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus agalactiae.

Linezolid is a synthetic antibacterial agent of a new class of antibiotics, the oxazolidinones, which has clinical utility in the treatment of infections caused by aerobic Gram-positive bacteria. The in vitro spectrum of activity of linezolid also includes certain Gram-negative bacteria and anaerobic bacteria. Susceptible organisms include methicillin- and vancomycin-resistant staphylococci, vancomycin-resistant enterococci, penicillin-resistant pneumococci and anaerobes. Oxazolidinones inhibit protein synthesis by binding at the P site at the ribosomal 50S subunit. Resistance to other protein synthesis inhibitors does not affect oxazolidinone activity, however rare development of oxazolidinone resistance cases, associated with 23S rRNA alterations during treatment have been reported. Linezolid inhibits bacterial protein synthesis through a mechanism of action different from that of other antibacterial agents; therefore, cross-resistance between linezolid and other classes of antibiotics is unlikely.

Linezolid is rapidly and extensively absorbed after oral dosing. Maximum plasma concentrations are reached approximately 1 to 2 hours after dosing, and the absolute bioavailability is approximately 100%.

Clinical signs of acute toxicity lead to decreased activity, ataxia, vomiting and tremors.

Gram negative and gram positive bacteria