L-Glutamine
Brand names,
L-Glutamine
Analogs
L-Glutamine
Brand Names Mixture
L-Glutamine
Chemical_Formula
C5H10N2O3
L-Glutamine
RX_link
No information avaliable
L-Glutamine
fda sheet
L-Glutamine
msds (material safety sheet)
L-Glutamine
Synthesis Reference
No information avaliable
L-Glutamine
Molecular Weight
146.146 g/mol
L-Glutamine
Melting Point
185 oC
L-Glutamine
H2O Solubility
Slight (0.1-1%)
L-Glutamine
State
Solid
L-Glutamine
LogP
-4.102
L-Glutamine
Dosage Forms
Capsules, powder, tablets
L-Glutamine
Indication
Used for nutritional supplementation, also for treating dietary shortage or imbalance.
L-Glutamine
Pharmacology
Like other amino acids, glutamine is biochemically important as a constituent of proteins. Glutamine is also crucial in nitrogen metabolism. Ammonia (formed by nitrogen fixation) is assimilated into organic compounds by converting glutamic acid to glutamine. The enzyme which accomplishes this is called glutamine synthetase. Glutamine can then be used as a nitrogen donor in the biosynthesis of many compounds, including other amino acids, purines, and pyrimidines.
L-Glutamine
Absorption
Absorption is efficient and occurs by an active transport mechanism
L-Glutamine
side effects and Toxicity
Doses of L-glutamine up to 21 grams daily appear to be well tolerated. Reported adverse reactions are mainly gastrointestinal and not common. They include constipation and bloating. There is one older report of two hypomanic patients whose manic symptoms were exacerbated following the use of 2 to 4 grams daily of L-glutamine. The symptoms resolved when the L-glutamine was stopped. These patients were not rechallenged, nor are there any other reports of this nature.
L-Glutamine
Patient Information
No information avaliable
L-Glutamine
Organisms Affected
Humans and other mammals