Glutamine
Glutamine Brand names, Glutamine Analogs
Glutamine Brand Names Mixture
- No information avaliable
Glutamine Chemical_Formula
C5H10N2O3
Glutamine RX_link
No information avaliable
Glutamine fda sheet
Glutamine msds (material safety sheet)
Glutamine Synthesis Reference
No information avaliable
Glutamine Molecular Weight
146.146 g/mol
Glutamine Melting Point
185 oC
Glutamine H2O Solubility
Slight (0.1-1%)
Glutamine State
Solid
Glutamine LogP
-4.102
Glutamine Dosage Forms
Capsules, powder, tablets
Glutamine Indication
Used for nutritional supplementation, also for treating dietary shortage or imbalance.
Glutamine Pharmacology
Like other amino acids, glutamine is biochemically important as a constituent of proteins. Glutamine is also crucial in nitrogen metabolism. Ammonia (formed by nitrogen fixation) is assimilated into organic compounds by converting glutamic acid to glutamine. The enzyme which accomplishes this is called glutamine synthetase. Glutamine can then be used as a nitrogen donor in the biosynthesis of many compounds, including other amino acids, purines, and pyrimidines.
Glutamine Absorption
Absorption is efficient and occurs by an active transport mechanism
Glutamine side effects and Toxicity
Doses of L-glutamine up to 21 grams daily appear to be well tolerated. Reported adverse reactions are mainly gastrointestinal and not common. They include constipation and bloating. There is one older report of two hypomanic patients whose manic symptoms were exacerbated following the use of 2 to 4 grams daily of L-glutamine. The symptoms resolved when the L-glutamine was stopped. These patients were not rechallenged, nor are there any other reports of this nature.
Glutamine Patient Information
No information avaliable
Glutamine Organisms Affected
Humans and other mammals
