2-Aminoglutaramic acid
Brand names,
2-Aminoglutaramic acid
Analogs
2-Aminoglutaramic acid
Brand Names Mixture
2-Aminoglutaramic acid
Chemical_Formula
C5H10N2O3
2-Aminoglutaramic acid
RX_link
No information avaliable
2-Aminoglutaramic acid
fda sheet
2-Aminoglutaramic acid
msds (material safety sheet)
2-Aminoglutaramic acid
Synthesis Reference
No information avaliable
2-Aminoglutaramic acid
Molecular Weight
146.146 g/mol
2-Aminoglutaramic acid
Melting Point
185 oC
2-Aminoglutaramic acid
H2O Solubility
Slight (0.1-1%)
2-Aminoglutaramic acid
State
Solid
2-Aminoglutaramic acid
LogP
-4.102
2-Aminoglutaramic acid
Dosage Forms
Capsules, powder, tablets
2-Aminoglutaramic acid
Indication
Used for nutritional supplementation, also for treating dietary shortage or imbalance.
2-Aminoglutaramic acid
Pharmacology
Like other amino acids, glutamine is biochemically important as a constituent of proteins. Glutamine is also crucial in nitrogen metabolism. Ammonia (formed by nitrogen fixation) is assimilated into organic compounds by converting glutamic acid to glutamine. The enzyme which accomplishes this is called glutamine synthetase. Glutamine can then be used as a nitrogen donor in the biosynthesis of many compounds, including other amino acids, purines, and pyrimidines.
2-Aminoglutaramic acid
Absorption
Absorption is efficient and occurs by an active transport mechanism
2-Aminoglutaramic acid
side effects and Toxicity
Doses of L-glutamine up to 21 grams daily appear to be well tolerated. Reported adverse reactions are mainly gastrointestinal and not common. They include constipation and bloating. There is one older report of two hypomanic patients whose manic symptoms were exacerbated following the use of 2 to 4 grams daily of L-glutamine. The symptoms resolved when the L-glutamine was stopped. These patients were not rechallenged, nor are there any other reports of this nature.
2-Aminoglutaramic acid
Patient Information
No information avaliable
2-Aminoglutaramic acid
Organisms Affected
Humans and other mammals