L-(-)-Methionine
L-(-)-Methionine Brand names, L-(-)-Methionine Analogs
L-(-)-Methionine Brand Names Mixture
- No information avaliable
L-(-)-Methionine Chemical_Formula
C5H11N1O2S1
L-(-)-Methionine RX_link
No information avaliable
L-(-)-Methionine fda sheet
L-(-)-Methionine msds (material safety sheet)
L-(-)-Methionine Synthesis Reference
No information avaliable
L-(-)-Methionine Molecular Weight
149.207 g/mol
L-(-)-Methionine Melting Point
276-279 oC
L-(-)-Methionine H2O Solubility
No information avaliable
L-(-)-Methionine State
Solid
L-(-)-Methionine LogP
-2.308
L-(-)-Methionine Dosage Forms
Capsules, powder and tablets
L-(-)-Methionine Indication
Used for protein synthesis including the formation of SAMe, L-homocysteine, L-cysteine, taurine, and sulfate.
L-(-)-Methionine Pharmacology
Is a principle supplier of sulfur which prevents disorders of the hair, skin and nails; helps lower cholesterol levels by increasing the liver's production of lecithin; reduces liver fat and protects the kidneys; a natural chelating agent for heavy metals; regulates the formation of ammonia and creates ammonia-free urine which reduces bladder irritation; influences hair follicles and promotes hair growth. L-methionine may protect against the toxic effects of hepatotoxins, such as acetaminophen. Methionine may have antioxidant activity.
L-(-)-Methionine Absorption
Absorbed from the lumen of the small intestine into the enterocytes by an active transport process.
L-(-)-Methionine side effects and Toxicity
Doses of L-methionine of up to 250 mg daily are generally well tolerated. Higher doses may cause nausea, vomiting and headache. Healthy adults taking 8 grams of L-methionine daily for four days were found to have reduced serum folate levels and leucocytosis. Healthy adults taking 13.9 grams of L-methionine daily for five days were found to have changes in serum pH and potassium and increased urinary calcium excretion. Schizophrenic patients given 10 to 20 grams of L-methionine daily for two weeks developed functional psychoses. Single doses of 8 grams precipitated encephalopathy in patients with cirrhosis.
L-(-)-Methionine Patient Information
There are no indications for the use of supplemental methionine unless specifically recommended by a physician. It is effective as an antidote in some cases of acetaminophen poisoning. But, because some research suggests that it may promote some cancers, its use as a supplement is inadvisable.
L-(-)-Methionine Organisms Affected
Humans and other mammals
