L( )-Aminobernsteinsaeure
Brand names,
L( )-Aminobernsteinsaeure
Analogs
L( )-Aminobernsteinsaeure
Brand Names Mixture
L( )-Aminobernsteinsaeure
Chemical_Formula
C4H7N1O4
L( )-Aminobernsteinsaeure
RX_link
No information avaliable
L( )-Aminobernsteinsaeure
fda sheet
L( )-Aminobernsteinsaeure
msds (material safety sheet)
L( )-Aminobernsteinsaeure
Synthesis Reference
No information avaliable
L( )-Aminobernsteinsaeure
Molecular Weight
133.104 g/mol
L( )-Aminobernsteinsaeure
Melting Point
230 oC
L( )-Aminobernsteinsaeure
H2O Solubility
4.5 g/l
L( )-Aminobernsteinsaeure
State
Solid
L( )-Aminobernsteinsaeure
LogP
-0.67 +/- 0.36
L( )-Aminobernsteinsaeure
Dosage Forms
Capsules and powder
L( )-Aminobernsteinsaeure
Indication
There is no support for the claim that aspartates are exercise performance enhancers, i.e. ergogenic aids.
L( )-Aminobernsteinsaeure
Pharmacology
L-aspartate is considered a non-essential amino acid, meaning that, under normal physiological conditions, sufficient amounts of the amino acid are synthesized in the body to meet the body's requirements. L-aspartate is formed by the transamination of the Krebs cycle intermediate oxaloacetate. The amino acid serves as a precursor for synthesis of proteins, oligopeptides, purines, pyrimidines, nucleic acids and L-arginine. L-aspartate is a glycogenic amino acid, and it can also promote energy production via its metabolism in the Krebs cycle. These latter activities were the rationale for the claim that supplemental aspartate has an anti-fatigue effect on skeletal muscle, a claim that was never confirmed.
L( )-Aminobernsteinsaeure
Absorption
Absorbed from the small intestine by an active transport process
L( )-Aminobernsteinsaeure
side effects and Toxicity
Mild gastrointestinal side effects including diarrhea. LD50 (rat) > 5,000 mg/kg.
L( )-Aminobernsteinsaeure
Patient Information
No information avaliable
L( )-Aminobernsteinsaeure
Organisms Affected
Humans and other mammals