CCRIs 6181
Brand names,
CCRIs 6181
Analogs
CCRIs 6181
Brand Names Mixture
CCRIs 6181
Chemical_Formula
C4H7N1O4
CCRIs 6181
RX_link
No information avaliable
CCRIs 6181
fda sheet
CCRIs 6181
msds (material safety sheet)
CCRIs 6181
Synthesis Reference
No information avaliable
CCRIs 6181
Molecular Weight
133.104 g/mol
CCRIs 6181
Melting Point
230 oC
CCRIs 6181
H2O Solubility
4.5 g/l
CCRIs 6181
State
Solid
CCRIs 6181
LogP
-0.67 +/- 0.36
CCRIs 6181
Dosage Forms
Capsules and powder
CCRIs 6181
Indication
There is no support for the claim that aspartates are exercise performance enhancers, i.e. ergogenic aids.
CCRIs 6181
Pharmacology
L-aspartate is considered a non-essential amino acid, meaning that, under normal physiological conditions, sufficient amounts of the amino acid are synthesized in the body to meet the body's requirements. L-aspartate is formed by the transamination of the Krebs cycle intermediate oxaloacetate. The amino acid serves as a precursor for synthesis of proteins, oligopeptides, purines, pyrimidines, nucleic acids and L-arginine. L-aspartate is a glycogenic amino acid, and it can also promote energy production via its metabolism in the Krebs cycle. These latter activities were the rationale for the claim that supplemental aspartate has an anti-fatigue effect on skeletal muscle, a claim that was never confirmed.
CCRIs 6181
Absorption
Absorbed from the small intestine by an active transport process
CCRIs 6181
side effects and Toxicity
Mild gastrointestinal side effects including diarrhea. LD50 (rat) > 5,000 mg/kg.
CCRIs 6181
Patient Information
No information avaliable
CCRIs 6181
Organisms Affected
Humans and other mammals