HSDB 1430
Brand names,
HSDB 1430
Analogs
HSDB 1430
Brand Names Mixture
HSDB 1430
Chemical_Formula
C4H7N1O4
HSDB 1430
RX_link
No information avaliable
HSDB 1430
fda sheet
HSDB 1430
msds (material safety sheet)
HSDB 1430
Synthesis Reference
No information avaliable
HSDB 1430
Molecular Weight
133.104 g/mol
HSDB 1430
Melting Point
230 oC
HSDB 1430
H2O Solubility
4.5 g/l
HSDB 1430
State
Solid
HSDB 1430
LogP
-0.67 +/- 0.36
HSDB 1430
Dosage Forms
Capsules and powder
HSDB 1430
Indication
There is no support for the claim that aspartates are exercise performance enhancers, i.e. ergogenic aids.
HSDB 1430
Pharmacology
L-aspartate is considered a non-essential amino acid, meaning that, under normal physiological conditions, sufficient amounts of the amino acid are synthesized in the body to meet the body's requirements. L-aspartate is formed by the transamination of the Krebs cycle intermediate oxaloacetate. The amino acid serves as a precursor for synthesis of proteins, oligopeptides, purines, pyrimidines, nucleic acids and L-arginine. L-aspartate is a glycogenic amino acid, and it can also promote energy production via its metabolism in the Krebs cycle. These latter activities were the rationale for the claim that supplemental aspartate has an anti-fatigue effect on skeletal muscle, a claim that was never confirmed.
HSDB 1430
Absorption
Absorbed from the small intestine by an active transport process
HSDB 1430
side effects and Toxicity
Mild gastrointestinal side effects including diarrhea. LD50 (rat) > 5,000 mg/kg.
HSDB 1430
Patient Information
No information avaliable
HSDB 1430
Organisms Affected
Humans and other mammals