AI3-04461
Brand names,
AI3-04461
Analogs
AI3-04461
Brand Names Mixture
AI3-04461
Chemical_Formula
C4H7N1O4
AI3-04461
RX_link
No information avaliable
AI3-04461
fda sheet
AI3-04461
msds (material safety sheet)
AI3-04461
Synthesis Reference
No information avaliable
AI3-04461
Molecular Weight
133.104 g/mol
AI3-04461
Melting Point
230 oC
AI3-04461
H2O Solubility
4.5 g/l
AI3-04461
State
Solid
AI3-04461
LogP
-0.67 +/- 0.36
AI3-04461
Dosage Forms
Capsules and powder
AI3-04461
Indication
There is no support for the claim that aspartates are exercise performance enhancers, i.e. ergogenic aids.
AI3-04461
Pharmacology
L-aspartate is considered a non-essential amino acid, meaning that, under normal physiological conditions, sufficient amounts of the amino acid are synthesized in the body to meet the body's requirements. L-aspartate is formed by the transamination of the Krebs cycle intermediate oxaloacetate. The amino acid serves as a precursor for synthesis of proteins, oligopeptides, purines, pyrimidines, nucleic acids and L-arginine. L-aspartate is a glycogenic amino acid, and it can also promote energy production via its metabolism in the Krebs cycle. These latter activities were the rationale for the claim that supplemental aspartate has an anti-fatigue effect on skeletal muscle, a claim that was never confirmed.
AI3-04461
Absorption
Absorbed from the small intestine by an active transport process
AI3-04461
side effects and Toxicity
Mild gastrointestinal side effects including diarrhea. LD50 (rat) > 5,000 mg/kg.
AI3-04461
Patient Information
No information avaliable
AI3-04461
Organisms Affected
Humans and other mammals