Ibutilide
Ibutilide Brand names, Ibutilide Analogs
Ibutilide Brand Names Mixture
- No information avaliable
Ibutilide Chemical_Formula
C20H36N2O3S
Ibutilide RX_link
http://www.rxlist.com/cgi/generic3/ibutilide.htm
Ibutilide fda sheet
Ibutilide msds (material safety sheet)
Ibutilide Synthesis Reference
No information avaliable
Ibutilide Molecular Weight
384.578 g/mol
Ibutilide Melting Point
No information avaliable
Ibutilide H2O Solubility
100 mg/mL
Ibutilide State
Solid
Ibutilide LogP
5.756
Ibutilide Dosage Forms
Solution (for injection); Suspension
Ibutilide Indication
Indicated for the rapid conversion of atrial fibrillation or atrial flutter of recent onset to sinus rhythm.
Ibutilide Pharmacology
Ibutilide fumurate prolongs the action potential duration and increases both atrial and ventricular refractoriness in vivo, i.e., class III electrophysiologic effects. Voltage clamp studies indicate that Ibutilide, at nanomolar concentrations, delays repolarization by activation of a slow, inward current (predominantly sodium), rather than by blocking outward potassium currents, which is the mechanism by which most other class III antiarrhythmics act.
Ibutilide Absorption
Rapid after intravenous injection
Ibutilide side effects and Toxicity
No information avaliable
Ibutilide Patient Information
No information avaliable
Ibutilide Organisms Affected
Humans and other mammals
