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Corvert Chemical_Formula


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Corvert Molecular Weight

384.578 g/mol

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Corvert H2O Solubility

100 mg/mL

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Corvert Dosage Forms

Solution (for injection); Suspension

Corvert Indication

Indicated for the rapid conversion of atrial fibrillation or atrial flutter of recent onset to sinus rhythm.

Corvert Pharmacology

Ibutilide fumurate prolongs the action potential duration and increases both atrial and ventricular refractoriness in vivo, i.e., class III electrophysiologic effects. Voltage clamp studies indicate that Ibutilide, at nanomolar concentrations, delays repolarization by activation of a slow, inward current (predominantly sodium), rather than by blocking outward potassium currents, which is the mechanism by which most other class III antiarrhythmics act.

Corvert Absorption

Rapid after intravenous injection

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Corvert Organisms Affected

Humans and other mammals