Etomidate
Etomidate Brand names, Etomidate Analogs
Etomidate Brand Names Mixture
- No information avaliable
Etomidate Chemical_Formula
C14H16N2O2
Etomidate RX_link
No information avaliable
Etomidate fda sheet
Etomidate msds (material safety sheet)
Etomidate Synthesis Reference
No information avaliable
Etomidate Molecular Weight
244.289 g/mol
Etomidate Melting Point
67 oC
Etomidate H2O Solubility
63.2 mg/L
Etomidate State
Solid
Etomidate LogP
2.695
Etomidate Dosage Forms
Solution for injection (2 mg/mL)
Etomidate Indication
Used in the induction of general anesthesia.
Etomidate Pharmacology
Etomidate is a non-barbiturate hypnotic that acts at the level of the reticular-activating system to produce anesthesia. Etomidate is an imidazole compound that appears to depress CNS function via GABA. Duration of action is intermediate between thiopental and methohexital, and recovery from a single dose is rapid with little residual depression. Like the barbiturates and propofol, etomidate is does not induce analgesia. Etomidate induces unconsciousness within one circulation time. Recovery is rapid as a result of extensive redistribution and rapid metabolism.
Etomidate Absorption
No information avaliable
Etomidate side effects and Toxicity
Undesirable side effects of etomidate that may limit its use include pain on injection, myoclonus and adrenocortical suppression lasting 4-6 hours following an induction dose.
Etomidate Patient Information
No information avaliable
Etomidate Organisms Affected
Humans and other mammals
