Ethinimate
Brand names,
Ethinimate
Analogs
Ethinimate
Brand Names Mixture
Ethinimate
Chemical_Formula
C14H16N2O2
Ethinimate
RX_link
No information avaliable
Ethinimate
fda sheet
Ethinimate
msds (material safety sheet)
Ethinimate
Synthesis Reference
No information avaliable
Ethinimate
Molecular Weight
244.289 g/mol
Ethinimate
Melting Point
67 oC
Ethinimate
H2O Solubility
63.2 mg/L
Ethinimate
State
Solid
Ethinimate
LogP
2.695
Ethinimate
Dosage Forms
Solution for injection (2 mg/mL)
Ethinimate
Indication
Used in the induction of general anesthesia.
Ethinimate
Pharmacology
Etomidate is a non-barbiturate hypnotic that acts at the level of the reticular-activating system to produce anesthesia. Etomidate is an imidazole compound that appears to depress CNS function via GABA. Duration of action is intermediate between thiopental and methohexital, and recovery from a single dose is rapid with little residual depression. Like the barbiturates and propofol, etomidate is does not induce analgesia. Etomidate induces unconsciousness within one circulation time. Recovery is rapid as a result of extensive redistribution and rapid metabolism.
Ethinimate
Absorption
No information avaliable
Ethinimate
side effects and Toxicity
Undesirable side effects of etomidate that may limit its use include pain on injection, myoclonus and adrenocortical suppression lasting 4-6 hours following an induction dose.
Ethinimate
Patient Information
No information avaliable
Ethinimate
Organisms Affected
Humans and other mammals