Valmidate
Brand names,
Valmidate
Analogs
Valmidate
Brand Names Mixture
Valmidate
Chemical_Formula
C14H16N2O2
Valmidate
RX_link
No information avaliable
Valmidate
fda sheet
Valmidate
msds (material safety sheet)
Valmidate
Synthesis Reference
No information avaliable
Valmidate
Molecular Weight
244.289 g/mol
Valmidate
Melting Point
67 oC
Valmidate
H2O Solubility
63.2 mg/L
Valmidate
State
Solid
Valmidate
LogP
2.695
Valmidate
Dosage Forms
Solution for injection (2 mg/mL)
Valmidate
Indication
Used in the induction of general anesthesia.
Valmidate
Pharmacology
Etomidate is a non-barbiturate hypnotic that acts at the level of the reticular-activating system to produce anesthesia. Etomidate is an imidazole compound that appears to depress CNS function via GABA. Duration of action is intermediate between thiopental and methohexital, and recovery from a single dose is rapid with little residual depression. Like the barbiturates and propofol, etomidate is does not induce analgesia. Etomidate induces unconsciousness within one circulation time. Recovery is rapid as a result of extensive redistribution and rapid metabolism.
Valmidate
Absorption
No information avaliable
Valmidate
side effects and Toxicity
Undesirable side effects of etomidate that may limit its use include pain on injection, myoclonus and adrenocortical suppression lasting 4-6 hours following an induction dose.
Valmidate
Patient Information
No information avaliable
Valmidate
Organisms Affected
Humans and other mammals