Econazole
Econazole Brand names, Econazole Analogs
Econazole Brand Names Mixture
- No information avaliable
Econazole Chemical_Formula
C18H15Cl3N2O
Econazole RX_link
http://www.rxlist.com/cgi/generic3/econazole.htm
Econazole fda sheet
Econazole msds (material safety sheet)
Econazole Synthesis Reference
No information avaliable
Econazole Molecular Weight
381.683 g/mol
Econazole Melting Point
No information avaliable
Econazole H2O Solubility
No information avaliable
Econazole State
No information avaliable
Econazole LogP
5.401
Econazole Dosage Forms
Topical cream (1%); Suppository
Econazole Indication
For topical application in the treatment of tinea pedis, tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Microsporum canis, Microsporum audouini, Microsporum gypseum, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis, and in the treatment of tinea versicolor.
Econazole Pharmacology
Econazole is an antifungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and clotrimazole (Lotrimin, Mycelex). Econazole prevents fungal organisms from producing vital substances required for growth and function. This medication is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Econazole Absorption
After topical application to the skin of normal subjects, systemic absorption of econazole nitrate is extremely low. Although most of the applied drug remains on the skin surface, drug concentrations were found in the stratum corneum which, by far, exceeded the minimum inhibitory concentration for dermatophytes.
Econazole side effects and Toxicity
Overdosage of econazole in humans has not been reported to date. In mice, rats guinea pigs and dogs, the oral LD 50 values were found to be 462, 668, 272, and > 160 mg/kg, respectively.
Econazole Patient Information
No information avaliable
Econazole Organisms Affected
Yeast and other fungi
