Medrotestron propionate
Brand names,
Medrotestron propionate
Analogs
Medrotestron propionate
Brand Names Mixture
Medrotestron propionate
Chemical_Formula
C18H15Cl3N2O
Medrotestron propionate
RX_link
http://www.rxlist.com/cgi/generic3/econazole.htm
Medrotestron propionate
fda sheet
Medrotestron propionate
msds (material safety sheet)
Medrotestron propionate
Synthesis Reference
No information avaliable
Medrotestron propionate
Molecular Weight
381.683 g/mol
Medrotestron propionate
Melting Point
No information avaliable
Medrotestron propionate
H2O Solubility
No information avaliable
Medrotestron propionate
State
No information avaliable
Medrotestron propionate
LogP
5.401
Medrotestron propionate
Dosage Forms
Topical cream (1%); Suppository
Medrotestron propionate
Indication
For topical application in the treatment of tinea pedis, tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Microsporum canis, Microsporum audouini, Microsporum gypseum, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis, and in the treatment of tinea versicolor.
Medrotestron propionate
Pharmacology
Econazole is an antifungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and clotrimazole (Lotrimin, Mycelex). Econazole prevents fungal organisms from producing vital substances required for growth and function. This medication is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Medrotestron propionate
Absorption
After topical application to the skin of normal subjects, systemic absorption of econazole nitrate is extremely low. Although most of the applied drug remains on the skin surface, drug concentrations were found in the stratum corneum which, by far, exceeded the minimum inhibitory concentration for dermatophytes.
Medrotestron propionate
side effects and Toxicity
Overdosage of econazole in humans has not been reported to date. In mice, rats guinea pigs and dogs, the oral LD 50 values were found to be 462, 668, 272, and > 160 mg/kg, respectively.
Medrotestron propionate
Patient Information
No information avaliable
Medrotestron propionate
Organisms Affected
Yeast and other fungi