Emdisterone
Emdisterone Brand names, Emdisterone Analogs
Emdisterone Brand Names Mixture
- No information avaliable
Emdisterone Chemical_Formula
C18H15Cl3N2O
Emdisterone RX_link
http://www.rxlist.com/cgi/generic3/econazole.htm
Emdisterone fda sheet
Emdisterone msds (material safety sheet)
Emdisterone Synthesis Reference
No information avaliable
Emdisterone Molecular Weight
381.683 g/mol
Emdisterone Melting Point
No information avaliable
Emdisterone H2O Solubility
No information avaliable
Emdisterone State
No information avaliable
Emdisterone LogP
5.401
Emdisterone Dosage Forms
Topical cream (1%); Suppository
Emdisterone Indication
For topical application in the treatment of tinea pedis, tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Microsporum canis, Microsporum audouini, Microsporum gypseum, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis, and in the treatment of tinea versicolor.
Emdisterone Pharmacology
Econazole is an antifungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and clotrimazole (Lotrimin, Mycelex). Econazole prevents fungal organisms from producing vital substances required for growth and function. This medication is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Emdisterone Absorption
After topical application to the skin of normal subjects, systemic absorption of econazole nitrate is extremely low. Although most of the applied drug remains on the skin surface, drug concentrations were found in the stratum corneum which, by far, exceeded the minimum inhibitory concentration for dermatophytes.
Emdisterone side effects and Toxicity
Overdosage of econazole in humans has not been reported to date. In mice, rats guinea pigs and dogs, the oral LD 50 values were found to be 462, 668, 272, and > 160 mg/kg, respectively.
Emdisterone Patient Information
No information avaliable
Emdisterone Organisms Affected
Yeast and other fungi
