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Brand names,
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Analogs
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Brand Names Mixture
- Alesse 21 Tablets (Ethinyl Estradiol + Levonorgestrel)
- Alesse 28 Tablets (Ethinyl Estradiol + Levonorgestrel)
- Brevicon 0.5/35 21 Tab (Ethinyl Estradiol + Norethindrone)
- Brevicon 0.5/35 28 Tab (Ethinyl Estradiol + Norethindrone)
- Brevicon 0.5/35 Tablets (21-Day Pack) (Ethinyl Estradiol + Norethindrone)
- Brevicon 0.5/35 Tablets (28-Day Pack) (Ethinyl Estradiol + Norethindrone)
- Brevicon 1/35 21 Tab (Ethinyl Estradiol + Norethindrone)
- Brevicon 1/35 28 Tab (Ethinyl Estradiol + Norethindrone)
- Brevicon 1/35 Tablets (21-Day Pack) (Ethinyl Estradiol + Norethindrone)
- Brevicon 1/35 Tablets (28-Day Pack) (Ethinyl Estradiol + Norethindrone)
- Cyclen Tablets (21 Day) (Ethinyl Estradiol + Norgestimate)
- Cyclen Tablets (28 Day) (Ethinyl Estradiol + Norgestimate)
- Demulen 30 (21 Day Pack) (Ethinyl Estradiol + Ethynodiol Diacetate)
- Demulen 30 (28 Day Pack) (Ethinyl Estradiol + Ethynodiol Diacetate)
- Demulen 50 (21 Day Pack) (Ethinyl Estradiol + Ethynodiol Diacetate)
- Demulen 50 (28 Day Pack) (Ethinyl Estradiol + Ethynodiol Diacetate)
- Diane-35 (Cyproterone Acetate + Ethinyl Estradiol)
- Evra -(6/0.60) (Ethinyl Estradiol + Norelgestromin)
- Evra -(6/0.75) (Ethinyl Estradiol + Norelgestromin)
- Femhrt 1/5 (Ethinyl Estradiol + Norethindrone Acetate)
- Geri Bons Tab (Calcium (Calcium Phosphate (Dibasic)) + Copper + Dl-Methionine + Ethinyl Estradiol + Fatty Acids + Folic Acid + Iodine + Iron Peptonized + Magnesium + Manganese + Methyltestosterone + Nicotinamide + Phosphorus (Calcium Phosphate (Dibasic)) + Pyridoxine Hydrochloride + Thiamine Hydrochloride + Thyroid + Vitamin a + Vitamin B12 + Vitamin B2 + Vitamin D + Vitamin E)
- Geri Tabs (Calcium (Calcium Phosphate (Dibasic)) + Copper Sulfate + Dl-Methionine + Ethinyl Estradiol + Folic Acid + Iodine + Iron Peptonized + Magnesium Oxide + Manganese Sulfate + Methyltestosterone + Nicotinamide + Phosphorus (Calcium Phosphate (Dibasic)) + Pyridoxine Hydrochloride + Thiamine Hydrochloride + Thyroid + Vitamin a + Vitamin B12 + Vitamin B2 + Vitamin D + Vitamin E)
- Lo-Femenal 21 Tablets (Ethinyl Estradiol + Norgestrel)
- Loestrin 1.5/30 21day Pak (Ethinyl Estradiol + Norethindrone Acetate)
- Loestrin 1.5/30 28day Pack (Ethinyl Estradiol + Norethindrone Acetate)
- Marvelon 21 Tab (Desogestrel + Ethinyl Estradiol)
- Marvelon 28 Tab (Desogestrel + Ethinyl Estradiol)
- Min-Ovral 21 (Ethinyl Estradiol + Levonorgestrel)
- Min-Ovral 21 Tab (Ethinyl Estradiol + Levonorgestrel)
- Min-Ovral 28 (Ethinyl Estradiol + Levonorgestrel)
- Min-Ovral 28 Tab (Ethinyl Estradiol + Levonorgestrel)
- Minestrin 1/20 21 (Ethinyl Estradiol + Norethindrone Acetate)
- Minestrin 1/20 28 (Ethinyl Estradiol + Norethindrone Acetate)
- Neo Mens Tab (Ethinyl Estradiol + Ethisterone)
- Nuvaring (Ethinyl Estradiol + Etonogestrel)
- Ortho 0.5/35 Tablets (21 Day) (Ethinyl Estradiol + Norethindrone)
- Ortho 0.5/35 Tablets (28day) (Ethinyl Estradiol + Norethindrone)
- Ortho 1/35 Tablets (21 Day) (Ethinyl Estradiol + Norethindrone)
- Ortho 1/35 Tablets (28 Day) (Ethinyl Estradiol + Norethindrone)
- Ortho 10/11 Tablets (21 Day) (Ethinyl Estradiol + Norethindrone)
- Ortho 10/11 Tablets (28 Day) (Ethinyl Estradiol + Norethindrone)
- Ortho 7/7/7 Tablets (21 Day) (Ethinyl Estradiol + Norethindrone)
- Ortho 7/7/7 Tablets (28 Day) (Ethinyl Estradiol + Norethindrone)
- Ortho-Cept Tablets (21 Day) (Desogestrel + Ethinyl Estradiol)
- Ortho-Cept Tablets (28 Day) (Desogestrel + Ethinyl Estradiol)
- Ovral 21 Tab (Ethinyl Estradiol + Norgestrel (Norgestrel))
- Ovral 21 Tablets (Ethinyl Estradiol + Norgestrel (Norgestrel))
- Ovral 28 Tablets (Ethinyl Estradiol + Norgestrel (Norgestrel))
- Ovral 28tab (Ethinyl Estradiol + Norgestrel)
- Preven Tablets (Ethinyl Estradiol + Levonorgestrel)
- Select 1/35 (21-Day) (Ethinyl Estradiol + Norethindrone)
- Select 1/35 (28-Day) (Ethinyl Estradiol + Norethindrone)
- Synphasic 21 Tablets (Ethinyl Estradiol + Norethindrone)
- Synphasic 28 Tablets (Ethinyl Estradiol + Norethindrone)
- Synphasic-28 Tablets (Ethinyl Estradiol + Norethindrone)
- Tri-Cyclen Lo (-21 Day Not Part of Product Name) (Ethinyl Estradiol + Norgestimate)
- Tri-Cyclen Lo (-28 Day Not Part of Product Name) (Ethinyl Estradiol + Norgestimate)
- Tri-Cyclen Tablets - 21-Day (Ethinyl Estradiol + Norgestimate)
- Tri-Cyclen Tablets - 28-Day (Ethinyl Estradiol + Norgestimate)
- Triphasil 21 (Ethinyl Estradiol + Levonorgestrel)
- Triphasil 21 Tab (Ethinyl Estradiol + Levonorgestrel)
- Triphasil 28 (Ethinyl Estradiol + Levonorgestrel)
- Triphasil 28 Tab (Ethinyl Estradiol + Levonorgestrel)
- Triquilar 21 Tab (Ethinyl Estradiol + Levonorgestrel)
- Triquilar 28 Tab (Ethinyl Estradiol + Levonorgestrel)
- Yasmin 21 (Drospirenone + Ethinyl Estradiol)
- Yasmin 28 (Drospirenone + Ethinyl Estradiol)
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Chemical_Formula
C20H24O2
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RX_link
http://www.rxlist.com/cgi/generic3/estinyl.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
Inhofen et al., Ber. 71, 1024(1938)
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Molecular Weight
296.403 g/mol
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Melting Point
183 oC
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H2O Solubility
11.3 mg/L
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State
Solid
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LogP
3.731
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Dosage Forms
Disc (sustained-release); Gel; Implant; Liquid; Patch; Ring (slow-release); Solution; Tablet
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Indication
For treatment of moderate to severe vasomotor symptoms associated with the menopause, female hypogonadism, prostatic carcinoma-palliative therapy of advanced disease, breast cancer, as an oral contraceptive, and as emergency contraceptive.
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Pharmacology
Ethinyl estradiol is a synthetic derivative of the natural estrogen estradiol. It is one of two estrogens currently used in oral contraceptive pills. The other, mestranol, is converted to ethinyl estradiol before it is biologically active. Ethinyl estradiol and norethindrone are used together as an oral contraceptive agent.
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Absorption
Rapid and complete absorption follows oral intake of ethinyl estradiol (bioavailability 43%).
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side effects and Toxicity
Oral, mouse LD50: 1737 mg/kg. Symptoms of overdose include nausea and vomiting, and withdrawal bleeding may occur in females.
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Patient Information
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Organisms Affected
Humans and other mammals