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Duloxetine Brand names, Duloxetine Analogs

Duloxetine Brand Names Mixture

  • No information avaliable

Duloxetine Chemical_Formula


Duloxetine RX_link


Duloxetine fda sheet

Duloxetine FDA

Duloxetine msds (material safety sheet)

Duloxetine MSDS

Duloxetine Synthesis Reference

No information avaliable

Duloxetine Molecular Weight

297.416 g/mol

Duloxetine Melting Point

No information avaliable

Duloxetine H2O Solubility

Slightly soluble

Duloxetine State


Duloxetine LogP


Duloxetine Dosage Forms


Duloxetine Indication

For the treatment of major depressive disorder (MDD).

Duloxetine Pharmacology

Duloxetine is in a class of medications called selective serotonin and norepinephrine reuptake inhibitors (SSNRIs) and primarily targets major depressive disorders (MDD) and stress urinary incontinence (SUI). Duloxetine is also used to treat pain and tingling caused by diabetic neuropathy (damage to nerves that can develop in people who have diabetes). Known also as LY248686, it is a potent dual inhibitor of serotonin (5-hydroxytryptamine, 5-HT) and norepinephrine (NE) reuptake, possessing comparable affinities in binding to NE and 5-HT transport sites. Interestingly, its behavior contrasts to most other dual-reuptake inhibitors. Furthermore, duloxentine lacks affinity for monoamine receptors within the central nervous system.

Duloxetine Absorption

Orally administered duloxetine hydrochloride is well absorbed.

Duloxetine side effects and Toxicity

Oral, rat LD50: 491 mg/kg for males and 279 mg/kg for females. Symptoms of overdose include tremors, convulsions, reduced activity, slow pupillary response, intermittent tremors, and rigidity.

Duloxetine Patient Information

No information avaliable

Duloxetine Organisms Affected

Humans and other mammals