Cymbalta
Cymbalta Brand names, Cymbalta Analogs
Cymbalta Brand Names Mixture
- No information avaliable
Cymbalta Chemical_Formula
C18H19NOS
Cymbalta RX_link
http://www.rxlist.com/cgi/generic/cymbalta.htm
Cymbalta fda sheet
Cymbalta msds (material safety sheet)
Cymbalta Synthesis Reference
No information avaliable
Cymbalta Molecular Weight
297.416 g/mol
Cymbalta Melting Point
No information avaliable
Cymbalta H2O Solubility
Slightly soluble
Cymbalta State
Solid
Cymbalta LogP
5.024
Cymbalta Dosage Forms
Capsule
Cymbalta Indication
For the treatment of major depressive disorder (MDD).
Cymbalta Pharmacology
Duloxetine is in a class of medications called selective serotonin and norepinephrine reuptake inhibitors (SSNRIs) and primarily targets major depressive disorders (MDD) and stress urinary incontinence (SUI). Duloxetine is also used to treat pain and tingling caused by diabetic neuropathy (damage to nerves that can develop in people who have diabetes). Known also as LY248686, it is a potent dual inhibitor of serotonin (5-hydroxytryptamine, 5-HT) and norepinephrine (NE) reuptake, possessing comparable affinities in binding to NE and 5-HT transport sites. Interestingly, its behavior contrasts to most other dual-reuptake inhibitors. Furthermore, duloxentine lacks affinity for monoamine receptors within the central nervous system.
Cymbalta Absorption
Orally administered duloxetine hydrochloride is well absorbed.
Cymbalta side effects and Toxicity
Oral, rat LD50: 491 mg/kg for males and 279 mg/kg for females. Symptoms of overdose include tremors, convulsions, reduced activity, slow pupillary response, intermittent tremors, and rigidity.
Cymbalta Patient Information
No information avaliable
Cymbalta Organisms Affected
Humans and other mammals
