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Yentreve Brand names, Yentreve Analogs

Yentreve Brand Names Mixture

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Yentreve Chemical_Formula


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Yentreve Synthesis Reference

No information avaliable

Yentreve Molecular Weight

297.416 g/mol

Yentreve Melting Point

No information avaliable

Yentreve H2O Solubility

Slightly soluble

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Yentreve Indication

For the treatment of major depressive disorder (MDD).

Yentreve Pharmacology

Duloxetine is in a class of medications called selective serotonin and norepinephrine reuptake inhibitors (SSNRIs) and primarily targets major depressive disorders (MDD) and stress urinary incontinence (SUI). Duloxetine is also used to treat pain and tingling caused by diabetic neuropathy (damage to nerves that can develop in people who have diabetes). Known also as LY248686, it is a potent dual inhibitor of serotonin (5-hydroxytryptamine, 5-HT) and norepinephrine (NE) reuptake, possessing comparable affinities in binding to NE and 5-HT transport sites. Interestingly, its behavior contrasts to most other dual-reuptake inhibitors. Furthermore, duloxentine lacks affinity for monoamine receptors within the central nervous system.

Yentreve Absorption

Orally administered duloxetine hydrochloride is well absorbed.

Yentreve side effects and Toxicity

Oral, rat LD50: 491 mg/kg for males and 279 mg/kg for females. Symptoms of overdose include tremors, convulsions, reduced activity, slow pupillary response, intermittent tremors, and rigidity.

Yentreve Patient Information

No information avaliable

Yentreve Organisms Affected

Humans and other mammals