Yentreve
Yentreve Brand names, Yentreve Analogs
Yentreve Brand Names Mixture
- No information avaliable
Yentreve Chemical_Formula
C18H19NOS
Yentreve RX_link
http://www.rxlist.com/cgi/generic/cymbalta.htm
Yentreve fda sheet
Yentreve msds (material safety sheet)
Yentreve Synthesis Reference
No information avaliable
Yentreve Molecular Weight
297.416 g/mol
Yentreve Melting Point
No information avaliable
Yentreve H2O Solubility
Slightly soluble
Yentreve State
Solid
Yentreve LogP
5.024
Yentreve Dosage Forms
Capsule
Yentreve Indication
For the treatment of major depressive disorder (MDD).
Yentreve Pharmacology
Duloxetine is in a class of medications called selective serotonin and norepinephrine reuptake inhibitors (SSNRIs) and primarily targets major depressive disorders (MDD) and stress urinary incontinence (SUI). Duloxetine is also used to treat pain and tingling caused by diabetic neuropathy (damage to nerves that can develop in people who have diabetes). Known also as LY248686, it is a potent dual inhibitor of serotonin (5-hydroxytryptamine, 5-HT) and norepinephrine (NE) reuptake, possessing comparable affinities in binding to NE and 5-HT transport sites. Interestingly, its behavior contrasts to most other dual-reuptake inhibitors. Furthermore, duloxentine lacks affinity for monoamine receptors within the central nervous system.
Yentreve Absorption
Orally administered duloxetine hydrochloride is well absorbed.
Yentreve side effects and Toxicity
Oral, rat LD50: 491 mg/kg for males and 279 mg/kg for females. Symptoms of overdose include tremors, convulsions, reduced activity, slow pupillary response, intermittent tremors, and rigidity.
Yentreve Patient Information
No information avaliable
Yentreve Organisms Affected
Humans and other mammals
