Disoprivan
Disoprivan Brand names, Disoprivan Analogs
Disoprivan Brand Names Mixture
- No information avaliable
Disoprivan Chemical_Formula
C47H64N4O12
Disoprivan RX_link
http://www.rxlist.com/cgi/generic/priftin.htm
Disoprivan fda sheet
Disoprivan msds (material safety sheet)
Disoprivan Synthesis Reference
No information avaliable
Disoprivan Molecular Weight
877.031 g/mol
Disoprivan Melting Point
No information avaliable
Disoprivan H2O Solubility
No information avaliable
Disoprivan State
Solid
Disoprivan LogP
5.29
Disoprivan Dosage Forms
No information avaliable
Disoprivan Indication
For the treatment of pulmonary tuberculosis.
Disoprivan Pharmacology
Rifapentine is an antibiotic that inhibits DNA-dependent RNA polymerase activity in susceptible cells. Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme. It is bactericidal and has a very broad spectrum of activity against most gram-positive and gram-negative organisms (including Pseudomonas aeruginosa) and specifically Mycobacterium tuberculosis. Because of rapid emergence of resistant bacteria, use is restricted to treatment of mycobacterial infections and a few other indications. Rifampin is well absorbed when taken orally and is distributed widely in body tissues and fluids, including the CSF. It is metabolized in the liver and eliminated in bile and, to a much lesser extent, in urine, but dose adjustments are unnecessary with renal insufficiency.
Disoprivan Absorption
Rapidly and well absorbed from the gastrointestinal tract.
Disoprivan side effects and Toxicity
No information avaliable
Disoprivan Patient Information
No information avaliable
Disoprivan Organisms Affected
Mycobacterium
