Diprivan
Brand names,
Diprivan
Analogs
Diprivan
Brand Names Mixture
Diprivan
Chemical_Formula
C47H64N4O12
Diprivan
RX_link
http://www.rxlist.com/cgi/generic/priftin.htm
Diprivan
fda sheet
Diprivan
msds (material safety sheet)
Diprivan
Synthesis Reference
No information avaliable
Diprivan
Molecular Weight
877.031 g/mol
Diprivan
Melting Point
No information avaliable
Diprivan
H2O Solubility
No information avaliable
Diprivan
State
Solid
Diprivan
LogP
5.29
Diprivan
Dosage Forms
No information avaliable
Diprivan
Indication
For the treatment of pulmonary tuberculosis.
Diprivan
Pharmacology
Rifapentine is an antibiotic that inhibits DNA-dependent RNA polymerase activity in susceptible cells. Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme. It is bactericidal and has a very broad spectrum of activity against most gram-positive and gram-negative organisms (including Pseudomonas aeruginosa) and specifically Mycobacterium tuberculosis. Because of rapid emergence of resistant bacteria, use is restricted to treatment of mycobacterial infections and a few other indications. Rifampin is well absorbed when taken orally and is distributed widely in body tissues and fluids, including the CSF. It is metabolized in the liver and eliminated in bile and, to a much lesser extent, in urine, but dose adjustments are unnecessary with renal insufficiency.
Diprivan
Absorption
Rapidly and well absorbed from the gastrointestinal tract.
Diprivan
side effects and Toxicity
No information avaliable
Diprivan
Patient Information
No information avaliable
Diprivan
Organisms Affected
Mycobacterium