Dilactone Actinomycindioic D Acid
Dilactone Actinomycindioic D Acid Brand names, Dilactone Actinomycindioic D Acid Analogs
- ACT
- ACT D
- ACTINOMYCIN D
- ACTO-D
- AD
- Actactinomycin a Iv
- Actinomycin 11 Cosmegen
- Actinomycin 7
- Actinomycin Aiv
- Actinomycin C1
- Actinomycin I
- Actinomycin I1
- Actinomycin Iv
- Actinomycin X 1
- Actinomycindioic D Acid, Dilactone
- Antibiotic From Streptomyces Parvullus
- Chounghwamycin B
- Cosmegen
- Dactinomicina [Inn-Spanish]
- Dactinomycin D
- Dactinomycin [Usan:Ban]
- Dactinomycine [Inn-French]
- Dactinomycinum [Inn-Latin]
- Dilactone Actinomycin D Acid
- Dilactone Actinomycindioic D Acid
- Hbf 386 Meractinomycin
- Lyovac Cosmegen
- Meractinomycin
- Oncostatin K
- Oxamide
Dilactone Actinomycindioic D Acid Brand Names Mixture
- No information avaliable
Dilactone Actinomycindioic D Acid Chemical_Formula
C62H86N12O16
Dilactone Actinomycindioic D Acid RX_link
http://www.rxlist.com/cgi/generic2/dactinomycin.htm
Dilactone Actinomycindioic D Acid fda sheet
Dilactone Actinomycindioic D Acid msds (material safety sheet)
Dilactone Actinomycindioic D Acid Synthesis Reference
Brockmann et al; Chem.Ber.; 93; 2971,2975(1960)
Dilactone Actinomycindioic D Acid Molecular Weight
1255.42 g/mol
Dilactone Actinomycindioic D Acid Melting Point
241.5 - 243 oC
Dilactone Actinomycindioic D Acid H2O Solubility
Soluble at 10°C
Dilactone Actinomycindioic D Acid State
solid
Dilactone Actinomycindioic D Acid LogP
0.517
Dilactone Actinomycindioic D Acid Dosage Forms
Injectable and parenteral solution
Dilactone Actinomycindioic D Acid Indication
For the treatment of Wilms' tumor, childhood rhabdomyosarcoma, Ewing's sarcoma and metastatic, nonseminomatous testicular cancer as part of a combination chemotherapy and/or multi-modality treatment regimen
Dilactone Actinomycindioic D Acid Pharmacology
Generally, the actinomycins exert an inhibitory effect on gram-positive and gram-negative bacteria and on some fungi. However, the toxic properties of the actinomycins (including dactinomycin) in relation to antibacterial activity are such as to preclude their use as antibiotics in the treatment of infectious diseases. Because the actinomycins are cytotoxic, they have an antineoplastic effect which has been demonstrated in experimental animals with various types of tumor implant. This cytotoxic action is the basis for their use in the treatment of certain types of cancer. Dactinomycin is believed to produce its cytotoxic effects by binding DNA and inhibiting RNA synthesis.
Dilactone Actinomycindioic D Acid Absorption
poorly absorbed from gastrointestinal tract
Dilactone Actinomycindioic D Acid side effects and Toxicity
hepatoxicity
Dilactone Actinomycindioic D Acid Patient Information
Dactinomycin is a type of antibiotic that is only used in cancer
chemotherapy. It slows or stops the growth of cancer cells in your
body. The length of treatment depends on the types of drugs you are
taking, how well your body responds to them, and the type of cancer
you have. tell your doctor and pharmacist if you are allergic to
dactinomycin or any other drugs. tell your doctor and pharmacist
what prescription and nonprescription medications you are taking,
especially aspirin and vitamins. tell your doctor if you have or
have ever had liver disease, ulcers, or gastrointestinal disease.
you should know that dactinomycin may interfere with the normal
menstrual cycle (period) in women and may stop sperm production
in men. However, you should not assume that you cannot get pregnant
or that you cannot get someone else pregnant. Women who are pregnant
or breast-feeding should tell their doctors before they begin taking
this drug. You should not plan to have children while receiving
chemotherapy or for a while after treatments. (Talk to your doctor
for further details.) Use a reliable method of birth control to
prevent pregnancy. Dactinomycin may harm the fetus. do not have any
vaccinations (e.g., measles or flu shots) without talking to your
doctor.
chemotherapy. It slows or stops the growth of cancer cells in your
body. The length of treatment depends on the types of drugs you are
taking, how well your body responds to them, and the type of cancer
you have. tell your doctor and pharmacist if you are allergic to
dactinomycin or any other drugs. tell your doctor and pharmacist
what prescription and nonprescription medications you are taking,
especially aspirin and vitamins. tell your doctor if you have or
have ever had liver disease, ulcers, or gastrointestinal disease.
you should know that dactinomycin may interfere with the normal
menstrual cycle (period) in women and may stop sperm production
in men. However, you should not assume that you cannot get pregnant
or that you cannot get someone else pregnant. Women who are pregnant
or breast-feeding should tell their doctors before they begin taking
this drug. You should not plan to have children while receiving
chemotherapy or for a while after treatments. (Talk to your doctor
for further details.) Use a reliable method of birth control to
prevent pregnancy. Dactinomycin may harm the fetus. do not have any
vaccinations (e.g., measles or flu shots) without talking to your
doctor.
Dilactone Actinomycindioic D Acid Organisms Affected
Humans and other mammals
