Desoximetasone

Desoximetasone Brand names, Desoximetasone Analogs

Desoximetasone Brand Names Mixture

No information avaliable

Desoximetasone Chemical_Formula

C₂₂H₂₉FO₄

Desoximetasone RX_link

http://www.rxlist.com/cgi/generic3/desoximeta.htm

Desoximetasone fda sheet

Desoximetasone FDA

Desoximetasone msds (material safety sheet)

Desoximetasone Synthesis Reference

No information avaliable

Desoximetasone Molecular Weight

376.462 g/mol

Desoximetasone Melting Point

217 ^oC

Desoximetasone H₂O Solubility

42.1 mg/L

Desoximetasone State

Solid

Desoximetasone LogP

2.031

Desoximetasone Dosage Forms

Emollient cream (0.25% or 0.05%); Gel; Ointment

Desoximetasone Indication

For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Desoximetasone Pharmacology

Like other topical corticosteroids, desoximetasone has anti-inflammatory, antipruritic, and vasoconstrictive properties. Once absorbed through the skin, topical corticosteroids are handled through pharmacokinetic pathways similar to systemically administered corticosteroids. Desoximetasone is a potent topical corticosteroid that should not be used with occlusive dressings. It is recommended that treatment should be limited to 2 consecutive weeks and therapy should be discontinued when adequate results have been achieved.

Desoximetasone Absorption

Topical corticosteroids can be absorbed from intact healthy skin. The extent of percutaneous absorption of topical corticosteroids is determined by many factors, including the vehicle and the integrity of the epidermal barrier. Occlusion, inflammation and/or other disease processes in the skin may also increase percutaneous absorption.

Desoximetasone side effects and Toxicity

Topically applied desoximetasone can be absorbed in sufficient amounts to produce systemic effects. Symptoms of overdose include thinning of skin and suppression of adrenal cortex (decreased ability to respond to stress).

Desoximetasone Patient Information