Topicort

Topicort Brand names, Topicort Analogs

Topicort Brand Names Mixture

No information avaliable

Topicort Chemical_Formula

C₂₂H₂₉FO₄

Topicort RX_link

http://www.rxlist.com/cgi/generic3/desoximeta.htm

Topicort fda sheet

Topicort FDA

Topicort msds (material safety sheet)

Topicort Synthesis Reference

No information avaliable

Topicort Molecular Weight

376.462 g/mol

Topicort Melting Point

217 ^oC

Topicort H₂O Solubility

42.1 mg/L

Topicort State

Solid

Topicort LogP

2.031

Topicort Dosage Forms

Emollient cream (0.25% or 0.05%); Gel; Ointment

Topicort Indication

For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Topicort Pharmacology

Like other topical corticosteroids, desoximetasone has anti-inflammatory, antipruritic, and vasoconstrictive properties. Once absorbed through the skin, topical corticosteroids are handled through pharmacokinetic pathways similar to systemically administered corticosteroids. Desoximetasone is a potent topical corticosteroid that should not be used with occlusive dressings. It is recommended that treatment should be limited to 2 consecutive weeks and therapy should be discontinued when adequate results have been achieved.

Topicort Absorption

Topical corticosteroids can be absorbed from intact healthy skin. The extent of percutaneous absorption of topical corticosteroids is determined by many factors, including the vehicle and the integrity of the epidermal barrier. Occlusion, inflammation and/or other disease processes in the skin may also increase percutaneous absorption.

Topicort side effects and Toxicity

Topically applied desoximetasone can be absorbed in sufficient amounts to produce systemic effects. Symptoms of overdose include thinning of skin and suppression of adrenal cortex (decreased ability to respond to stress).

Topicort Patient Information