Demadex

Demadex Brand names, Demadex Analogs

Demadex Brand Names Mixture

No information avaliable

Demadex Chemical_Formula

C₁₆H₂₀N₄O₃S

Demadex RX_link

http://www.rxlist.com/cgi/generic/demadex.htm

Demadex fda sheet

Demadex msds (material safety sheet)

Demadex MSDS

Demadex Synthesis Reference

No information avaliable

Demadex Molecular Weight

348.421 g/mol

Demadex Melting Point

163-164 ^oC (decomposition)

Demadex H₂O Solubility

Soluble

Demadex State

Solid

Demadex LogP

2.404

Demadex Dosage Forms

Liquid; Tablet

Demadex Indication

For the treatment of hypertension, edema induced by congestive heart failure or renal disease, and ascites associated with hepatic disease.

Demadex Pharmacology

Torasemide, a monosulfonamyl loop diuretic, differs form other thiazide diuretics in that a double ring system is incorporated into its structure. Torasemide is used alone or with atenolol in the management of hypertension and edema. Micropuncture studies in animals have shown that torsemide acts from within the lumen of the thick ascending portion of the loop of Henle, where it inhibits the Na⁺/K⁺/2Cl^--carrier system.

Demadex Absorption

Bioavailability is approximately 80%. Serum concentration peaks after approximately 1 hour.

Demadex side effects and Toxicity

LD₅₀ = 5 g/kg (rat, oral), 500 mg/kg (rat, intravenous). Side effects include dizziness, headache, nausea and vomiting.

Demadex Patient Information