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Daclizumab Brand names, Daclizumab Analogs

Daclizumab Brand Names Mixture

  • No information avaliable

Daclizumab Chemical_Formula

C6332H9808N1678O1989S42

Daclizumab RX_link

http://www.rxlist.com/cgi/generic3/zenapax.htm

Daclizumab fda sheet

Daclizumab msds (material safety sheet)

Daclizumab Synthesis Reference

Sequence listed in humanized anti-Tac, PNAS 1989 with Queen, C, Tsurushita N, Hinton PR, Kumar S. Design of humanized antibodies: from anti-Tac to Zenapax. Methods. 2005 May;36(1):69-83.

Daclizumab Molecular Weight

142612.1

Daclizumab Melting Point

61 oC (FAB fragment), 71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).

Daclizumab H2O Solubility

No information avaliable

Daclizumab State

Liquid

Daclizumab LogP

-0.437

Daclizumab Dosage Forms

Solution (IV)

Daclizumab Indication

For prevention of renal transplant rejection

Daclizumab Pharmacology

Zenapax functions as an IL-2 receptor antagonist. Specifically it inhibits IL-2-mediated activation of lymphocytes, a critical pathway in the cellular immune response involved in allograft rejection.

Daclizumab Absorption

No information avaliable

Daclizumab side effects and Toxicity

No information avaliable

Daclizumab Patient Information

No information avaliable

Daclizumab Organisms Affected

Humans and other mammals