Daclizumab
Daclizumab Brand names, Daclizumab Analogs
Daclizumab Brand Names Mixture
- No information avaliable
Daclizumab Chemical_Formula
C6332H9808N1678O1989S42
Daclizumab RX_link
http://www.rxlist.com/cgi/generic3/zenapax.htm
Daclizumab fda sheet
Daclizumab msds (material safety sheet)
Daclizumab Synthesis Reference
Sequence listed in humanized anti-Tac, PNAS 1989 with Queen, C, Tsurushita N, Hinton PR, Kumar S. Design of humanized antibodies: from anti-Tac to Zenapax. Methods. 2005 May;36(1):69-83.
Daclizumab Molecular Weight
142612.1
Daclizumab Melting Point
61 oC (FAB fragment), 71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
Daclizumab H2O Solubility
No information avaliable
Daclizumab State
Liquid
Daclizumab LogP
-0.437
Daclizumab Dosage Forms
Solution (IV)
Daclizumab Indication
For prevention of renal transplant rejection
Daclizumab Pharmacology
Zenapax functions as an IL-2 receptor antagonist. Specifically it inhibits IL-2-mediated activation of lymphocytes, a critical pathway in the cellular immune response involved in allograft rejection.
Daclizumab Absorption
No information avaliable
Daclizumab side effects and Toxicity
No information avaliable
Daclizumab Patient Information
No information avaliable
Daclizumab Organisms Affected
Humans and other mammals
