Anti-IL-2
Anti-IL-2 Brand names, Anti-IL-2 Analogs
Anti-IL-2 Brand Names Mixture
- No information avaliable
Anti-IL-2 Chemical_Formula
C6332H9808N1678O1989S42
Anti-IL-2 RX_link
http://www.rxlist.com/cgi/generic3/zenapax.htm
Anti-IL-2 fda sheet
Anti-IL-2 msds (material safety sheet)
Anti-IL-2 Synthesis Reference
Sequence listed in humanized anti-Tac, PNAS 1989 with Queen, C, Tsurushita N, Hinton PR, Kumar S. Design of humanized antibodies: from anti-Tac to Zenapax. Methods. 2005 May;36(1):69-83.
Anti-IL-2 Molecular Weight
142612.1
Anti-IL-2 Melting Point
61 oC (FAB fragment), 71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
Anti-IL-2 H2O Solubility
No information avaliable
Anti-IL-2 State
Liquid
Anti-IL-2 LogP
-0.437
Anti-IL-2 Dosage Forms
Solution (IV)
Anti-IL-2 Indication
For prevention of renal transplant rejection
Anti-IL-2 Pharmacology
Zenapax functions as an IL-2 receptor antagonist. Specifically it inhibits IL-2-mediated activation of lymphocytes, a critical pathway in the cellular immune response involved in allograft rejection.
Anti-IL-2 Absorption
No information avaliable
Anti-IL-2 side effects and Toxicity
No information avaliable
Anti-IL-2 Patient Information
No information avaliable
Anti-IL-2 Organisms Affected
Humans and other mammals
