Cordarone Intravenous en es it fr

Cordarone Intravenous Brand names, Cordarone Intravenous Analogs

Cordarone Intravenous Brand Names Mixture

  • No information avaliable

Cordarone Intravenous Chemical_Formula


Cordarone Intravenous RX_link

Cordarone Intravenous fda sheet

Cordarone_Intravenous FDA

Cordarone Intravenous msds (material safety sheet)

Cordarone_Intravenous MSDS

Cordarone Intravenous Synthesis Reference

No information avaliable

Cordarone Intravenous Molecular Weight

645.312 g/mol

Cordarone Intravenous Melting Point

No information avaliable

Cordarone Intravenous H2O Solubility


Cordarone Intravenous State


Cordarone Intravenous LogP


Cordarone Intravenous Dosage Forms

Liquid; Solution; Tablet (200 mg and 400 mg)

Cordarone Intravenous Indication

Intravenously, for initiation of treatment and prophylaxis of frequently recurring ventricular fibrillation and hemodynamically unstable ventricular tachycardia in patients refractory to other therapy. Orally, for the treatment of life-threatening recurrent ventricular arrhythmias such as recurrent ventricular fibrillation and recurrent hemodynamically unstable ventricular tachycardia.

Cordarone Intravenous Pharmacology

Amiodarone belongs to a class of drugs called Vaughan-Williams Class III antiarrhythmic agents. It is used in the treatment of a wide range of cardiac tachyarhthmias, including both ventricular and supraventricular (atrial) arrhythmias. After intravenous administration in man, amiodarone relaxes vascular smooth muscle, reduces peripheral vascular resistance (afterload), and slightly increases cardiac index. Amiodarone prolongs phase 3 of the cardiac action potential. It has numerous other effects however, including actions that are similar to those of antiarrhythmic classes Ia, II, and IV. Amiodarone shows beta blocker-like and calcium channel blocker-like actions on the SA and AV nodes, increases the refractory period via sodium- and potassium-channel effects, and slows intra-cardiac conduction of the cardiac action potential, via sodium-channel effects.

Cordarone Intravenous Absorption

Slow and variable (about 20 to 55% of an oral dose is absorbed).

Cordarone Intravenous side effects and Toxicity

Intravenous, mouse: LD50 = 178 mg/kg. Some side effects have a significant mortality rate: specifically, hepatitis, exacerbation of asthma and congestive failure, and pneumonitis.

Cordarone Intravenous Patient Information

No information avaliable

Cordarone Intravenous Organisms Affected

Humans and other mammals