Cevimeline hydrochloride hemihydrate;
Cevimeline hydrochloride hemihydrate; Brand names, Cevimeline hydrochloride hemihydrate; Analogs
Cevimeline hydrochloride hemihydrate; Brand Names Mixture
- No information avaliable
Cevimeline hydrochloride hemihydrate; Chemical_Formula
C10H17NOS
Cevimeline hydrochloride hemihydrate; RX_link
http://www.rxlist.com/cgi/generic2/cevimeline.htm
Cevimeline hydrochloride hemihydrate; fda sheet
Cevimeline hydrochloride hemihydrate; msds (material safety sheet)
Cevimeline hydrochloride hemihydrate; Synthesis Reference
No information avaliable
Cevimeline hydrochloride hemihydrate; Molecular Weight
489.565 g/mol
Cevimeline hydrochloride hemihydrate; Melting Point
201-203 oC (HCl salt)
Cevimeline hydrochloride hemihydrate; H2O Solubility
Very soluble
Cevimeline hydrochloride hemihydrate; State
Solid
Cevimeline hydrochloride hemihydrate; LogP
No information avaliable
Cevimeline hydrochloride hemihydrate; Dosage Forms
Capsule (white, hard gelatin capsules of cevimeline hydrochloride containing 30 mg of cevimeline)
Cevimeline hydrochloride hemihydrate; Indication
For the treatment of symptoms of dry mouth in patients with Sjögren's Syndrome.
Cevimeline hydrochloride hemihydrate; Pharmacology
Cevimeline is a cholinergic agonist which binds to muscarinic receptors. Muscarinic agonists in sufficient dosage can increase secretion of exocrine glands, such as salivary and sweat glands and increase tone of the smooth muscle in the gastrointestinal and urinary tracts.
Cevimeline hydrochloride hemihydrate; Absorption
Rapidly absorbed with peak concentration after 1.5 to 2 hours
Cevimeline hydrochloride hemihydrate; side effects and Toxicity
No information avaliable
Cevimeline hydrochloride hemihydrate; Patient Information
Patients should be informed that cevimeline may cause visual disturbances, especially at night, that could impair their ability to drive safely. If a patient sweats excessively while taking cevimeline, dehydration may develop. The patient should drink extra water and consult a health care provider.
Cevimeline hydrochloride hemihydrate; Organisms Affected
Humans and other mammals
