Saligren
Saligren Brand names, Saligren Analogs
Saligren Brand Names Mixture
- No information avaliable
Saligren Chemical_Formula
C10H17NOS
Saligren RX_link
http://www.rxlist.com/cgi/generic2/cevimeline.htm
Saligren fda sheet
Saligren msds (material safety sheet)
Saligren Synthesis Reference
No information avaliable
Saligren Molecular Weight
489.565 g/mol
Saligren Melting Point
201-203 oC (HCl salt)
Saligren H2O Solubility
Very soluble
Saligren State
Solid
Saligren LogP
No information avaliable
Saligren Dosage Forms
Capsule (white, hard gelatin capsules of cevimeline hydrochloride containing 30 mg of cevimeline)
Saligren Indication
For the treatment of symptoms of dry mouth in patients with Sjögren's Syndrome.
Saligren Pharmacology
Cevimeline is a cholinergic agonist which binds to muscarinic receptors. Muscarinic agonists in sufficient dosage can increase secretion of exocrine glands, such as salivary and sweat glands and increase tone of the smooth muscle in the gastrointestinal and urinary tracts.
Saligren Absorption
Rapidly absorbed with peak concentration after 1.5 to 2 hours
Saligren side effects and Toxicity
No information avaliable
Saligren Patient Information
Patients should be informed that cevimeline may cause visual disturbances, especially at night, that could impair their ability to drive safely. If a patient sweats excessively while taking cevimeline, dehydration may develop. The patient should drink extra water and consult a health care provider.
Saligren Organisms Affected
Humans and other mammals
