Cevimeline hydrochloride hydrate
Brand names,
Cevimeline hydrochloride hydrate
Analogs
Cevimeline hydrochloride hydrate
Brand Names Mixture
Cevimeline hydrochloride hydrate
Chemical_Formula
C10H17NOS
Cevimeline hydrochloride hydrate
RX_link
http://www.rxlist.com/cgi/generic2/cevimeline.htm
Cevimeline hydrochloride hydrate
fda sheet
Cevimeline hydrochloride hydrate
msds (material safety sheet)
Cevimeline hydrochloride hydrate
Synthesis Reference
No information avaliable
Cevimeline hydrochloride hydrate
Molecular Weight
489.565 g/mol
Cevimeline hydrochloride hydrate
Melting Point
201-203 oC (HCl salt)
Cevimeline hydrochloride hydrate
H2O Solubility
Very soluble
Cevimeline hydrochloride hydrate
State
Solid
Cevimeline hydrochloride hydrate
LogP
No information avaliable
Cevimeline hydrochloride hydrate
Dosage Forms
Capsule (white, hard gelatin capsules of cevimeline hydrochloride containing 30 mg of cevimeline)
Cevimeline hydrochloride hydrate
Indication
For the treatment of symptoms of dry mouth in patients with Sjögren's Syndrome.
Cevimeline hydrochloride hydrate
Pharmacology
Cevimeline is a cholinergic agonist which binds to muscarinic receptors. Muscarinic agonists in sufficient dosage can increase secretion of exocrine glands, such as salivary and sweat glands and increase tone of the smooth muscle in the gastrointestinal and urinary tracts.
Cevimeline hydrochloride hydrate
Absorption
Rapidly absorbed with peak concentration after 1.5 to 2 hours
Cevimeline hydrochloride hydrate
side effects and Toxicity
No information avaliable
Cevimeline hydrochloride hydrate
Patient Information
Patients should be informed that cevimeline may cause visual disturbances, especially at night, that could impair their ability to drive safely. If a patient sweats excessively while taking cevimeline, dehydration may develop. The patient should drink extra water and consult a health care provider.
Cevimeline hydrochloride hydrate
Organisms Affected
Humans and other mammals