Evoxac
Brand names,
Evoxac
Analogs
Evoxac
Brand Names Mixture
Evoxac
Chemical_Formula
C10H17NOS
Evoxac
RX_link
http://www.rxlist.com/cgi/generic2/cevimeline.htm
Evoxac
fda sheet
Evoxac
msds (material safety sheet)
Evoxac
Synthesis Reference
No information avaliable
Evoxac
Molecular Weight
489.565 g/mol
Evoxac
Melting Point
201-203 oC (HCl salt)
Evoxac
H2O Solubility
Very soluble
Evoxac
State
Solid
Evoxac
LogP
No information avaliable
Evoxac
Dosage Forms
Capsule (white, hard gelatin capsules of cevimeline hydrochloride containing 30 mg of cevimeline)
Evoxac
Indication
For the treatment of symptoms of dry mouth in patients with Sjögren's Syndrome.
Evoxac
Pharmacology
Cevimeline is a cholinergic agonist which binds to muscarinic receptors. Muscarinic agonists in sufficient dosage can increase secretion of exocrine glands, such as salivary and sweat glands and increase tone of the smooth muscle in the gastrointestinal and urinary tracts.
Evoxac
Absorption
Rapidly absorbed with peak concentration after 1.5 to 2 hours
Evoxac
side effects and Toxicity
No information avaliable
Evoxac
Patient Information
Patients should be informed that cevimeline may cause visual disturbances, especially at night, that could impair their ability to drive safely. If a patient sweats excessively while taking cevimeline, dehydration may develop. The patient should drink extra water and consult a health care provider.
Evoxac
Organisms Affected
Humans and other mammals