Cevimeline
Brand names,
Cevimeline
Analogs
Cevimeline
Brand Names Mixture
Cevimeline
Chemical_Formula
C10H17NOS
Cevimeline
RX_link
http://www.rxlist.com/cgi/generic2/cevimeline.htm
Cevimeline
fda sheet
Cevimeline
msds (material safety sheet)
Cevimeline
Synthesis Reference
No information avaliable
Cevimeline
Molecular Weight
489.565 g/mol
Cevimeline
Melting Point
201-203 oC (HCl salt)
Cevimeline
H2O Solubility
Very soluble
Cevimeline
State
Solid
Cevimeline
LogP
No information avaliable
Cevimeline
Dosage Forms
Capsule (white, hard gelatin capsules of cevimeline hydrochloride containing 30 mg of cevimeline)
Cevimeline
Indication
For the treatment of symptoms of dry mouth in patients with Sjögren's Syndrome.
Cevimeline
Pharmacology
Cevimeline is a cholinergic agonist which binds to muscarinic receptors. Muscarinic agonists in sufficient dosage can increase secretion of exocrine glands, such as salivary and sweat glands and increase tone of the smooth muscle in the gastrointestinal and urinary tracts.
Cevimeline
Absorption
Rapidly absorbed with peak concentration after 1.5 to 2 hours
Cevimeline
side effects and Toxicity
No information avaliable
Cevimeline
Patient Information
Patients should be informed that cevimeline may cause visual disturbances, especially at night, that could impair their ability to drive safely. If a patient sweats excessively while taking cevimeline, dehydration may develop. The patient should drink extra water and consult a health care provider.
Cevimeline
Organisms Affected
Humans and other mammals