Cerivastatin
Cerivastatin Brand names, Cerivastatin Analogs
Cerivastatin Brand Names Mixture
- No information avaliable
Cerivastatin Chemical_Formula
C26H34FNO5
Cerivastatin RX_link
http://www.rxlist.com/cgi/generic2/cerivastat.htm
Cerivastatin fda sheet
Cerivastatin msds (material safety sheet)
Cerivastatin Synthesis Reference
Angerbauer R, Bischoff H, Steinke W and Ritter W (1994) BAY w 6228. Drugs Fut 19: 537-541.
Cerivastatin Molecular Weight
459.55 g/mol
Cerivastatin Melting Point
No information avaliable
Cerivastatin H2O Solubility
Highly solubility
Cerivastatin State
Solid
Cerivastatin LogP
4.669
Cerivastatin Dosage Forms
Tablet
Cerivastatin Indication
Used as an adjunct to diet for the reduction of elevated total and LDL cholesterol levels in patients with primary hypercholesterolemia and mixed dyslipidemia (Fredrickson Types IIa and IIb) when the response to dietary restriction of saturated fat and cholesterol and other non-pharmacological measures alone has been inadequate.
Cerivastatin Pharmacology
Cerivastatin, a competitive HMG-CoA reductase inhibitor effective in lowering LDL cholesterol and triglycerides, is used to treat primary hypercholesterolemia and mixed dyslipidemia (Fredrickson types IIa and IIb).
Cerivastatin Absorption
The mean absolute oral bioavailability 60% (range 39 - 101%).
Cerivastatin side effects and Toxicity
Rhabdomyolysis, liver concerns
Cerivastatin Patient Information
Patients should be advised to report promptly unexplained muscle pain, tenderness, or weakness, particularly if accompanied by malaise or fever.
Cerivastatin Organisms Affected
Humans and other mammals
