Cerivastatin, sodium salt
Cerivastatin, sodium salt Brand names, Cerivastatin, sodium salt Analogs
Cerivastatin, sodium salt Brand Names Mixture
- No information avaliable
Cerivastatin, sodium salt Chemical_Formula
C26H34FNO5
Cerivastatin, sodium salt RX_link
http://www.rxlist.com/cgi/generic2/cerivastat.htm
Cerivastatin, sodium salt fda sheet
Cerivastatin, sodium salt msds (material safety sheet)
Cerivastatin, sodium salt Synthesis Reference
Angerbauer R, Bischoff H, Steinke W and Ritter W (1994) BAY w 6228. Drugs Fut 19: 537-541.
Cerivastatin, sodium salt Molecular Weight
459.55 g/mol
Cerivastatin, sodium salt Melting Point
No information avaliable
Cerivastatin, sodium salt H2O Solubility
Highly solubility
Cerivastatin, sodium salt State
Solid
Cerivastatin, sodium salt LogP
4.669
Cerivastatin, sodium salt Dosage Forms
Tablet
Cerivastatin, sodium salt Indication
Used as an adjunct to diet for the reduction of elevated total and LDL cholesterol levels in patients with primary hypercholesterolemia and mixed dyslipidemia (Fredrickson Types IIa and IIb) when the response to dietary restriction of saturated fat and cholesterol and other non-pharmacological measures alone has been inadequate.
Cerivastatin, sodium salt Pharmacology
Cerivastatin, a competitive HMG-CoA reductase inhibitor effective in lowering LDL cholesterol and triglycerides, is used to treat primary hypercholesterolemia and mixed dyslipidemia (Fredrickson types IIa and IIb).
Cerivastatin, sodium salt Absorption
The mean absolute oral bioavailability 60% (range 39 - 101%).
Cerivastatin, sodium salt side effects and Toxicity
Rhabdomyolysis, liver concerns
Cerivastatin, sodium salt Patient Information
Patients should be advised to report promptly unexplained muscle pain, tenderness, or weakness, particularly if accompanied by malaise or fever.
Cerivastatin, sodium salt Organisms Affected
Humans and other mammals
