Lipobay
Lipobay Brand names, Lipobay Analogs
Lipobay Brand Names Mixture
- No information avaliable
Lipobay Chemical_Formula
C26H34FNO5
Lipobay RX_link
http://www.rxlist.com/cgi/generic2/cerivastat.htm
Lipobay fda sheet
Lipobay msds (material safety sheet)
Lipobay Synthesis Reference
Angerbauer R, Bischoff H, Steinke W and Ritter W (1994) BAY w 6228. Drugs Fut 19: 537-541.
Lipobay Molecular Weight
459.55 g/mol
Lipobay Melting Point
No information avaliable
Lipobay H2O Solubility
Highly solubility
Lipobay State
Solid
Lipobay LogP
4.669
Lipobay Dosage Forms
Tablet
Lipobay Indication
Used as an adjunct to diet for the reduction of elevated total and LDL cholesterol levels in patients with primary hypercholesterolemia and mixed dyslipidemia (Fredrickson Types IIa and IIb) when the response to dietary restriction of saturated fat and cholesterol and other non-pharmacological measures alone has been inadequate.
Lipobay Pharmacology
Cerivastatin, a competitive HMG-CoA reductase inhibitor effective in lowering LDL cholesterol and triglycerides, is used to treat primary hypercholesterolemia and mixed dyslipidemia (Fredrickson types IIa and IIb).
Lipobay Absorption
The mean absolute oral bioavailability 60% (range 39 - 101%).
Lipobay side effects and Toxicity
Rhabdomyolysis, liver concerns
Lipobay Patient Information
Patients should be advised to report promptly unexplained muscle pain, tenderness, or weakness, particularly if accompanied by malaise or fever.
Lipobay Organisms Affected
Humans and other mammals
