Cefzon (TN) en es it fr

Cefzon (TN) Brand names, Cefzon (TN) Analogs

Cefzon (TN) Brand Names Mixture

  • No information avaliable

Cefzon (TN) Chemical_Formula


Cefzon (TN) RX_link


Cefzon (TN) fda sheet

Cefzon_(TN) FDA

Cefzon (TN) msds (material safety sheet)

Cefzon_(TN) MSDS

Cefzon (TN) Synthesis Reference

No information avaliable

Cefzon (TN) Molecular Weight

395.416 g/mol

Cefzon (TN) Melting Point

No information avaliable

Cefzon (TN) H2O Solubility

No information avaliable

Cefzon (TN) State


Cefzon (TN) LogP


Cefzon (TN) Dosage Forms

Capsules for oral administration (300mg); Oral suspension (125mg per 5mL solution)

Cefzon (TN) Indication

For the treatment of the respiratory, skin, soft tissue, and ENT infections caused by H. influenzae (including b-lactamase producing strains), H. parainfluenzae (including b-lactamase producing strains), S. pneumoniae (penicillin-susceptible strains), S. pyogenes, S. aureus (including b-lactamase producing strains), and M. catarrhalis.

Cefzon (TN) Pharmacology

Cefdinir is a third generation cephalosporin with a broad spectrum of activity against enteric gram-negative rods. Cefdinir is stable in the presence of some, but not all, b-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins are susceptible to cefdinir. Cephalosporins work the same way as penicillins: they interfere with the peptidoglycan synthesis of the bacterial wall by inhibiting the final transpeptidation needed for the cross-links. This effect is bactericidal.

Cefzon (TN) Absorption

Maximal plasma cefdinir concentrations occur 2 to 4 hours postdose following capsule or suspension administration. Estimated bioavailability of cefdinir capsules is 21% following administration of a 300 mg capsule dose, and 16% following administration of a 600 mg capsule dose. Estimated absolute bioavailability of cefdinir suspension is 25%. Absorption is reduced by approximately 15% when administered with a high fat meal.

Cefzon (TN) side effects and Toxicity

Information on cefdinir overdosage in humans is not available. In acute rodent toxicity studies, a single oral 5600-mg/kg dose produced no adverse effects. Toxic signs and symptoms following overdosage with other b-lactam antibiotics have included nausea, vomiting, epigastric distress, diarrhea, and convulsions.

Cefzon (TN) Patient Information

Cefzon (TN) Organisms Affected

Enteric gram-negative rods