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Cefotaxime Brand names, Cefotaxime Analogs

Cefotaxime Brand Names Mixture

  • No information avaliable

Cefotaxime Chemical_Formula


Cefotaxime RX_link


Cefotaxime fda sheet

Cefotaxime FDA

Cefotaxime msds (material safety sheet)

Cefotaxime MSDS

Cefotaxime Synthesis Reference

No information avaliable

Cefotaxime Molecular Weight

455.468 g/mol

Cefotaxime Melting Point

No information avaliable

Cefotaxime H2O Solubility


Cefotaxime State


Cefotaxime LogP


Cefotaxime Dosage Forms

Injection and infusion

Cefotaxime Indication

Used to treat gonorrhoea, meningitis, and severe infections including infections of the kidney (pyelonephritis) and urinary system. Also used before an operation to prevent infection after surgery.

Cefotaxime Pharmacology

Cefotaxime is a third generation intravenous cephalosporin antibiotic. It has broad spectrum activity against Gram positive and Gram negative bacteria. It does not have activity against Pseudomonas aeruginosa. Cefotaxime works by inhibiting bacterial cell wall biosynthesis. A positive feature of cefotaxime is that it display a resistance to penicillinases and is useful to treat infections that are resistant to penicillin derivatives.

Cefotaxime Absorption

Rapidly absorbed following intramuscular injection.

Cefotaxime side effects and Toxicity

Adverse effects following overdosage include nausea, vomiting, epigastric distress, diarrhea, and convulsions. Oral rat LD50 is over 20,000 mg/kg while intravenous rat LD50 is over 7,000 mg/kg.

Cefotaxime Patient Information

No information avaliable

Cefotaxime Organisms Affected

Enteric bacteria and other eubacteria