Claforan
Claforan Brand names, Claforan Analogs
Claforan Brand Names Mixture
- No information avaliable
Claforan Chemical_Formula
C16H17N5O7S2
Claforan RX_link
http://www.rxlist.com/cgi/generic/cefotax.htm
Claforan fda sheet
Claforan msds (material safety sheet)
Claforan Synthesis Reference
No information avaliable
Claforan Molecular Weight
455.468 g/mol
Claforan Melting Point
No information avaliable
Claforan H2O Solubility
Soluble
Claforan State
Solid
Claforan LogP
-0.685
Claforan Dosage Forms
Injection and infusion
Claforan Indication
Used to treat gonorrhoea, meningitis, and severe infections including infections of the kidney (pyelonephritis) and urinary system. Also used before an operation to prevent infection after surgery.
Claforan Pharmacology
Cefotaxime is a third generation intravenous cephalosporin antibiotic. It has broad spectrum activity against Gram positive and Gram negative bacteria. It does not have activity against Pseudomonas aeruginosa. Cefotaxime works by inhibiting bacterial cell wall biosynthesis. A positive feature of cefotaxime is that it display a resistance to penicillinases and is useful to treat infections that are resistant to penicillin derivatives.
Claforan Absorption
Rapidly absorbed following intramuscular injection.
Claforan side effects and Toxicity
Adverse effects following overdosage include nausea, vomiting, epigastric distress, diarrhea, and convulsions. Oral rat LD50 is over 20,000 mg/kg while intravenous rat LD50 is over 7,000 mg/kg.
Claforan Patient Information
No information avaliable
Claforan Organisms Affected
Enteric bacteria and other eubacteria
