PharmacyCodes



Cefmetazolo [INN-Spanish] en es it fr

Cefmetazolo [INN-Spanish] Brand names, Cefmetazolo [INN-Spanish] Analogs

Cefmetazolo [INN-Spanish] Brand Names Mixture

  • No information avaliable

Cefmetazolo [INN-Spanish] Chemical_Formula

C15H17N7O5S3

Cefmetazolo [INN-Spanish] RX_link

No information avaliable

Cefmetazolo [INN-Spanish] fda sheet

Cefmetazolo [INN-Spanish] msds (material safety sheet)

Cefmetazolo_[INN-Spanish] MSDS

Cefmetazolo [INN-Spanish] Synthesis Reference

No information avaliable

Cefmetazolo [INN-Spanish] Molecular Weight

471.538 g/mol

Cefmetazolo [INN-Spanish] Melting Point

No information avaliable

Cefmetazolo [INN-Spanish] H2O Solubility

94.2 mg/L

Cefmetazolo [INN-Spanish] State

No information avaliable

Cefmetazolo [INN-Spanish] LogP

-1.063

Cefmetazolo [INN-Spanish] Dosage Forms

Solution for injection

Cefmetazolo [INN-Spanish] Indication

For the treatment of infections caused by susceptible organisms.

Cefmetazolo [INN-Spanish] Pharmacology

Cefmetazole is a second-generation cephalosporin. The cephalosporins are bactericidal drugs with both gram-positive and gram-negative activity. They inhibit bacterial cell wall synthesis in a way similar to the penicillins. Cefmetazole is more active than 1st-generation cephalosporins against indole-positive Proteus, Serratia, anaerobic gram-negative bacilli (including B. fragilis), and some E. coli, Klebsiella, and P. mirabilis, but is less active than cefoxitin or cefotetan against most gram-negative bacilli.

Cefmetazolo [INN-Spanish] Absorption

Bioavailability is approximately 100% following intramuscular injection.

Cefmetazolo [INN-Spanish] side effects and Toxicity

Oral LD50 in rats is 3,204 mg/kg. With other b-lactam antibiotics, adverse effects following overdosage have included nausea, vomiting, epigastric distress, diarrhea, and convulsions.

Cefmetazolo [INN-Spanish] Patient Information

No information avaliable

Cefmetazolo [INN-Spanish] Organisms Affected

Enteric bacteria and other eubacteria