Cefmetazole sodium
Cefmetazole sodium Brand names, Cefmetazole sodium Analogs
Cefmetazole sodium Brand Names Mixture
- No information avaliable
Cefmetazole sodium Chemical_Formula
C15H17N7O5S3
Cefmetazole sodium RX_link
No information avaliable
Cefmetazole sodium fda sheet
Cefmetazole sodium msds (material safety sheet)
Cefmetazole sodium Synthesis Reference
No information avaliable
Cefmetazole sodium Molecular Weight
471.538 g/mol
Cefmetazole sodium Melting Point
No information avaliable
Cefmetazole sodium H2O Solubility
94.2 mg/L
Cefmetazole sodium State
No information avaliable
Cefmetazole sodium LogP
-1.063
Cefmetazole sodium Dosage Forms
Solution for injection
Cefmetazole sodium Indication
For the treatment of infections caused by susceptible organisms.
Cefmetazole sodium Pharmacology
Cefmetazole is a second-generation cephalosporin. The cephalosporins are bactericidal drugs with both gram-positive and gram-negative activity. They inhibit bacterial cell wall synthesis in a way similar to the penicillins. Cefmetazole is more active than 1st-generation cephalosporins against indole-positive Proteus, Serratia, anaerobic gram-negative bacilli (including B. fragilis), and some E. coli, Klebsiella, and P. mirabilis, but is less active than cefoxitin or cefotetan against most gram-negative bacilli.
Cefmetazole sodium Absorption
Bioavailability is approximately 100% following intramuscular injection.
Cefmetazole sodium side effects and Toxicity
Oral LD50 in rats is 3,204 mg/kg. With other b-lactam antibiotics, adverse effects following overdosage have included nausea, vomiting, epigastric distress, diarrhea, and convulsions.
Cefmetazole sodium Patient Information
No information avaliable
Cefmetazole sodium Organisms Affected
Enteric bacteria and other eubacteria
