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Cefmetazole sodium Brand names, Cefmetazole sodium Analogs

Cefmetazole sodium Brand Names Mixture

  • No information avaliable

Cefmetazole sodium Chemical_Formula

C15H17N7O5S3

Cefmetazole sodium RX_link

No information avaliable

Cefmetazole sodium fda sheet

Cefmetazole sodium msds (material safety sheet)

Cefmetazole_sodium MSDS

Cefmetazole sodium Synthesis Reference

No information avaliable

Cefmetazole sodium Molecular Weight

471.538 g/mol

Cefmetazole sodium Melting Point

No information avaliable

Cefmetazole sodium H2O Solubility

94.2 mg/L

Cefmetazole sodium State

No information avaliable

Cefmetazole sodium LogP

-1.063

Cefmetazole sodium Dosage Forms

Solution for injection

Cefmetazole sodium Indication

For the treatment of infections caused by susceptible organisms.

Cefmetazole sodium Pharmacology

Cefmetazole is a second-generation cephalosporin. The cephalosporins are bactericidal drugs with both gram-positive and gram-negative activity. They inhibit bacterial cell wall synthesis in a way similar to the penicillins. Cefmetazole is more active than 1st-generation cephalosporins against indole-positive Proteus, Serratia, anaerobic gram-negative bacilli (including B. fragilis), and some E. coli, Klebsiella, and P. mirabilis, but is less active than cefoxitin or cefotetan against most gram-negative bacilli.

Cefmetazole sodium Absorption

Bioavailability is approximately 100% following intramuscular injection.

Cefmetazole sodium side effects and Toxicity

Oral LD50 in rats is 3,204 mg/kg. With other b-lactam antibiotics, adverse effects following overdosage have included nausea, vomiting, epigastric distress, diarrhea, and convulsions.

Cefmetazole sodium Patient Information

No information avaliable

Cefmetazole sodium Organisms Affected

Enteric bacteria and other eubacteria