CLS
CLS Brand names, CLS Analogs
CLS Brand Names Mixture
- No information avaliable
CLS Chemical_Formula
C13H16ClNO
CLS RX_link
http://www.rxlist.com/cgi/generic3/ketamine.htm
CLS fda sheet
CLS msds (material safety sheet)
CLS Synthesis Reference
No information avaliable
CLS Molecular Weight
237.725 g/mol
CLS Melting Point
92.5 oC
CLS H2O Solubility
No information avaliable
CLS State
Solid
CLS LogP
3.032
CLS Dosage Forms
Solution
CLS Indication
For use as the sole anesthetic agent for diagnostic and surgical procedures that do not require skeletal muscle relaxation.
CLS Pharmacology
Ketamine is a rapid-acting general anesthetic producing an anesthetic state characterized by profound analgesia, normal pharyngeal-laryngeal reflexes, normal or slightly enhanced skeletal muscle tone, cardiovascular and respiratory stimulation, and occasionally a transient and minimal respiratory depression. Ketamine is indicated as the sole anesthetic agent for diagnostic and surgical procedures that do not require skeletal muscle relaxation. The anesthetic state produced by Ketamine has been termed “dissociative anesthesia” in that it appears to selectively interrupt association pathways of the brain before producing somesthetic sensory blockade. It may selectively depress the thalamoneocortical system before significantly obtunding the more ancient cerebral centers and pathways (reticularactivating and limbic systems).
CLS Absorption
Rapidly absorbed following parenteral administration.
CLS side effects and Toxicity
No information avaliable
CLS Patient Information
PATIENT INFORMATION
Follow the links
http://www.rxlist.com/cgi/generic3/ketamine_pi.htm
http://www.rxlist.com/cgi/generic3/ketamine_wcp.htm
http://www.drugs.com/cons/Ketamine.html
Follow the links
http://www.rxlist.com/cgi/generic3/ketamine_pi.htm
http://www.rxlist.com/cgi/generic3/ketamine_wcp.htm
http://www.drugs.com/cons/Ketamine.html
CLS Organisms Affected
Humans and other mammals
